Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 1/20 | 0.59 |
| ▸ | CNR2 | P34972 | 1/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | HTR7 | P34969 | 5/20 | 0.38 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.36 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | TOP2A | P11388 | 1/20 | 0.36 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.36 |
| ▸ | SLC10A2 | Q12908 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | APLNR | P35414 | 2/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10976332 | 0.89 | CNR1 (0.60) | CNR1CNR2ALDH1A1GAAHPGD | |
| SCHEMBL11074709 | 0.85 | CNR1 (0.56) | CNR1CNR2L3MBTL1ALDH1A1GAA | |
| Hydrochloric Acid SCHEMBL10973139 | 0.83 | CNR1 (0.52) | CNR1CNR2ALDH1A1TOP2ATOP2B | |
| SCHEMBL10972699 | 0.82 | CNR1 (0.67) | CNR1CNR2ALDH1A1HPGDALOX15 | |
| SCHEMBL10974453 | 0.81 | CNR1 (0.69) | CNR1CNR2ALDH1A1HPGDALOX15 | |
| SCHEMBL11075891 | 0.81 | CNR1 (0.65) | CNR1CNR2L3MBTL1ALDH1A1HPGD | |
| SCHEMBL11080762 | 0.80 | CNR1 (0.67) | CNR1CNR2L3MBTL1ALDH1A1HPGD | |
| SCHEMBL10976108 | 0.80 | CNR1 (0.65) | CNR1CNR2ALDH1A1GAAHPGD | |
| SCHEMBL10974218 | 0.79 | CNR1 (0.66) | CNR1CNR2ALDH1A1GAAHPGD | |
| SCHEMBL11079598 | 0.79 | CNR1 (0.56) | CNR1CNR2L3MBTL1ALDH1A1HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0056637-B1 | 4(3H)-QUINAZOLINONE DERIVATIVES, PROCESS FOR PRODUCTION THEREOF AND PHARMACEUTICAL COMPOSITIONS COMPRISING SAID COMPOUNDS | Ishikawa, Masayuki (JP) | 1985-07-24 | — | — | EP | claimed |
| US-4451467-A | HYPOTENSIVE AGENTS | Ishikawa, Masayuki (JP) | 1984-05-29 | — | — | US | claimed |
| EP-0056637-A1 | 4(3H)-quinazolinone derivatives, process for production thereof and pharmaceutical compositions comprising said compounds | Ishikawa, Masayuki (JP) | 1982-07-28 | — | — | EP | claimed |