Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | MMP8 | P22894 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10976716 | 0.84 | MEN1 (0.33) | MEN1KMT2AMAPK1MMP8PKM | |
| SCHEMBL10972813 | 0.82 | MAPT (0.37) | MEN1KMT2AMAPK1MMP8PKM | |
| SCHEMBL8847820 | 0.78 | MMP8 (0.38) | ALOX15MEN1KMT2AMAPK1HTT | |
| SCHEMBL10975865 | 0.78 | MAPK1 (0.33) | ALOX15MEN1KMT2AMAPK1MMP8 | |
| SCHEMBL1885876 | 0.76 | MMP8 (0.36) | MEN1KMT2AMAPK1HTTMMP8 | |
| SCHEMBL15992227 | 0.74 | ALOX15 (0.38) | ALOX15MEN1KMT2AMAPK1HTT | |
| SCHEMBL11678264 | 0.73 | MMP8 (0.34) | MEN1KMT2AMMP8PKM | |
| SCHEMBL25979049 | 0.73 | MEN1 (0.44) | MEN1KMT2AHTTMMP8PKM | |
| SCHEMBL8705908 | 0.72 | MEN1 (0.36) | MEN1KMT2AMMP8PKM | |
| SCHEMBL8378912 | 0.71 | ALOX15 (0.38) | ALOX15MEN1KMT2AMAPK1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0046713-B1 | FLUORINATED PENTENE DIAMINE DERIVATIVES | MERRELL TORAUDE ET COMPAGNIE (FR) | 1985-12-27 | — | — | EP | disclosed |
| US-4439619-A | Fluorinated pentene diamine derivatives | MERRELL TORAUDE ET COMPAGNIE (FR) | 1984-03-27 | — | — | US | disclosed |
| EP-0046713-A1 | Fluorinated pentene diamine derivatives | MERRELL TORAUDE ET COMPAGNIE (FR) | 1982-03-03 | — | — | EP | disclosed |