Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | ALB | P02768 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.47 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.44 |
| ▸ | CAPN9 | O14815 | 1/20 | 0.44 |
| ▸ | CASP3 | P42574 | 1/20 | 0.44 |
| ▸ | PGR | P06401 | 3/20 | 0.43 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
| ▸ | GABRP | O00591 | 1/20 | 0.40 |
| ▸ | GABRD | O14764 | 1/20 | 0.40 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.40 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.40 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.40 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.40 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.40 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11394894 | 0.88 | LMNA (0.67) | LMNAMEN1KMT2AALBHPGD | |
| SCHEMBL11462262 | 0.87 | LMNA (0.48) | LMNAMEN1KMT2AALBHPGD | |
| SCHEMBL13284385 | 0.85 | LMNA (0.61) | LMNAMEN1KMT2AALBCHRM1 | |
| SCHEMBL10971587 | 0.84 | LMNA (0.54) | LMNAMEN1KMT2AALBHPGD | |
| SCHEMBL13284383 | 0.81 | LMNA (0.77) | LMNAMEN1KMT2AALBCHRM1 | |
| SCHEMBL2615324 | 0.79 | LMNA (0.56) | LMNAMEN1KMT2AALBCHRM1 | |
| SCHEMBL31365170 | 0.79 | LMNA (0.71) | LMNAMEN1KMT2AALBHPGD | |
| SCHEMBL2615325 | 0.78 | LMNA (0.73) | LMNAMEN1KMT2AALBCHRM1 | |
| SCHEMBL11462390 | 0.77 | LMNA (0.47) | LMNAMEN1KMT2AHPGDPDE4D | |
| SCHEMBL11463765 | 0.77 | LMNA (0.47) | LMNAMEN1KMT2AALBHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0158267-A2 | Pharmaceutical composition containing 5-(2-fluorophenyl)-1,3-dihydro-3-hydroxy-7-nitro- or 5-(2-fluorophenyl)-1,3-dihydro-3-hydroxy-1-methyl-7-nitro-2H-1,4-benzodiazepin-2-one and process for their preparation | Dolorgiet Beteiligungs-GmbH (DE) | 1985-10-16 | — | — | EP | disclosed |