Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.61 |
| ▸ | MEN1 | O00255 | 2/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.61 |
| ▸ | ALB | P02768 | 1/20 | 0.61 |
| ▸ | PGR | P06401 | 1/20 | 0.50 |
| ▸ | CCKBR | P32239 | 4/20 | 0.45 |
| ▸ | CCKAR | P32238 | 3/20 | 0.45 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.42 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.42 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.42 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.42 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.38 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.38 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.38 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.38 |
| ▸ | CDK2 | P24941 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2615324 | 0.92 | LMNA (0.56) | LMNAMEN1KMT2AALBPGR | |
| SCHEMBL2615325 | 0.92 | LMNA (0.73) | LMNAMEN1KMT2AALBPGR | |
| SCHEMBL13284383 | 0.90 | LMNA (0.77) | LMNAMEN1KMT2AALBPGR | |
| SCHEMBL10974232 | 0.85 | LMNA (0.52) | LMNAMEN1KMT2AALBPGR | |
| SCHEMBL11473985 | 0.84 | GABRA1 (0.43) | LMNAMEN1KMT2AALBCCKBR | |
| SCHEMBL13285139 | 0.83 | CCKBR (0.47) | LMNAMEN1KMT2AALBCCKBR | |
| SCHEMBL13284429 | 0.83 | LMNA (0.62) | LMNAMEN1KMT2AALBPGR | |
| SCHEMBL2631488 | 0.81 | LMNA (0.78) | LMNAMEN1KMT2AALBPGR | |
| SCHEMBL28348373 | 0.81 | LMNA (0.85) | LMNAMEN1KMT2AALBPGR | |
| SCHEMBL11633050 | 0.77 | LMNA (0.79) | LMNAMEN1KMT2AALBPGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010081036-A2 | FLUORINE CONTAINING COMPOUNDS AND METHODS OF USE THEREOF | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2010-07-15 | — | — | WO | disclosed |