Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | ESR1 | P03372 | 2/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.37 |
| ▸ | KDM1A | O60341 | 9/20 | 0.37 |
| ▸ | MAOB | P27338 | 9/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 7/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.33 |
| ▸ | CYP2B6 | P20813 | 3/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16705136 | 1.00 | CYP3A4 (0.40) | CYP3A4TDP1ESR1ESR2KDM1A | |
| SCHEMBL12090467 | 1.00 | CYP3A4 (0.40) | CYP3A4TDP1ESR1ESR2KDM1A | |
| SCHEMBL16704816 | 1.00 | CYP3A4 (0.40) | CYP3A4TDP1ESR1ESR2KDM1A | |
| SCHEMBL16704801 | 1.00 | CYP3A4 (0.40) | CYP3A4TDP1ESR1ESR2KDM1A | |
| SCHEMBL12093765 | 1.00 | CYP3A4 (0.40) | CYP3A4TDP1ESR1ESR2KDM1A | |
| SCHEMBL109753 | 0.84 | MAOB (0.46) | CYP3A4KDM1AMAOBKDM4ETSHR | |
| SCHEMBL200919 | 0.82 | KDM1A (0.55) | CYP3A4KDM1AMAOBKDM4ETSHR | |
| SCHEMBL6234699 | 0.82 | KDM1A (0.38) | TDP1KDM1AMAOBKDM4ETSHR | |
| SCHEMBL16530012 | 0.82 | KDM1A (0.38) | TDP1KDM1AMAOBKDM4ETSHR | |
| SCHEMBL21525759 | 0.78 | KDM1A (0.42) | KDM1AMAOBKDM4ETSHRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9556294-B2 | Magnetic particle-polymer hybrid materials with functionalized polymers derived from norbornenyl reagents | THE UNIVERSITY OF KANSAS (US) | 2017-01-31 | — | — | US | disclosed |
| US-9556294-B2 | Magnetic particle-polymer hybrid materials with functionalized polymers derived from norbornenyl reagents | THE UNIVERSITY OF KANSAS (US) | 2017-01-31 | — | — | US | disclosed |
| US-20150175725-A1 | MAGNETIC PARTICLE-POLYMER HYBRID MATERIALS WITH FUNCTIONALIZED POLYMERS DERIVED FROM NORBORNENYL REAGENTS | THE UNIVERSITY OF KANSAS (US) | 2015-06-25 | — | — | US | disclosed |
| US-20150175725-A1 | MAGNETIC PARTICLE-POLYMER HYBRID MATERIALS WITH FUNCTIONALIZED POLYMERS DERIVED FROM NORBORNENYL REAGENTS | THE UNIVERSITY OF KANSAS (US) | 2015-06-25 | — | — | US | disclosed |
| US-9035003-B2 | High capacity magnetic nanoparticles as supports for reagents and catalysts | THE UNIVERSITY OF KANSAS (US) | 2015-05-19 | — | — | US | disclosed |