Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.37 |
| ▸ | GFER | P55789 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 7/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.37 |
| ▸ | G6PD | P11413 | 1/20 | 0.37 |
| ▸ | LOX | P28300 | 1/20 | 0.36 |
| ▸ | LOXL3 | P58215 | 1/20 | 0.36 |
| ▸ | LOXL4 | Q96JB6 | 1/20 | 0.36 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 5/20 | 0.34 |
| ▸ | HPGD | P15428 | 4/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | MGLL | Q99685 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 5/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12140369 | 0.66 | ALDH1A1 (0.36) | ALDH1A1GFERGAAL3MBTL1G6PD | |
| SCHEMBL18290913 | 0.66 | ALDH1A1 (0.36) | ALDH1A1GFERGAAL3MBTL1G6PD | |
| SCHEMBL5180030 | 0.60 | LOX (0.46) | ALDH1A1GFERGAAL3MBTL1G6PD | |
| Hydrochloric Acid SCHEMBL11038033 | 0.60 | ALDH1A1 (0.37) | ALDH1A1GFERGAAL3MBTL1G6PD | |
| SCHEMBL19000724 | 0.59 | NPC1 (0.36) | ALDH1A1GAAL3MBTL1MAPTHPGD | |
| SCHEMBL5903097 | 0.58 | CA12 (0.41) | ALDH1A1GAAL3MBTL1G6PDLOX | |
| SCHEMBL27488591 | 0.58 | LOX (0.37) | ALDH1A1GFERGAAL3MBTL1G6PD | |
| SCHEMBL28149550 | 0.57 | GAA (0.35) | ALDH1A1GAAL3MBTL1G6PDLOX | |
| SCHEMBL456215 | 0.57 | GAA (0.58) | ALDH1A1GFERGAALOXLOXL3 | |
| SCHEMBL28148422 | 0.57 | RIPK1 (0.37) | ALDH1A1GAAL3MBTL1G6PDLOX |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0056938-B1 | PROCESS FOR THE PREPARATION OF 3,6-DISUBSTITUTED 4-AMINO-1,2,4-TRIAZIN-5-ONES | BAYER AG (DE) | 1985-03-27 | — | — | EP | disclosed |