Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | KAT2B | Q92831 | 3/20 | 0.40 |
| ▸ | GHSR | Q92847 | 1/20 | 0.39 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MIF | P14174 | 1/20 | 0.36 |
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10971190 | 0.95 | MAPK1 (0.51) | MAPK1TSHRKAT2BGHSRP2RX7 | |
| SCHEMBL10974169 | 0.82 | MAPK1 (0.46) | MAPK1TSHRP2RX7ALDH1A1LMNA | |
| SCHEMBL13631407 | 0.78 | MAPK1 (0.72) | MAPK1TSHRALDH1A1LMNA | |
| SCHEMBL10968077 | 0.77 | KDM4E (0.50) | MAPK1TSHRP2RX7ALDH1A1LMNA | |
| SCHEMBL10969467 | 0.76 | HTT (0.51) | MAPK1TSHRP2RX7ALDH1A1LMNA | |
| SCHEMBL10972067 | 0.75 | HSD11B1 (0.60) | GHSRP2RX7ALDH1A1FAAH | |
| SCHEMBL10971909 | 0.74 | TLR7 (0.39) | MAPK1TSHRGHSRLMNAMIF | |
| SCHEMBL7499343 | 0.73 | CA12 (0.38) | — | |
| SCHEMBL2088514 | 0.72 | P2RX7 (0.46) | MAPK1P2RX7ALDH1A1LMNA | |
| SCHEMBL10677984 | 0.72 | TSHR (0.42) | TSHRKAT2BALDH1A1LMNAMIF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0035228-B1 | TETRAZOLE DERIVATIVES, PROCESS FOR THE PREPARATION THEREOF, AND ANTI-ULCER COMPOSITION CONTAINING THE SAME | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1985-01-02 | — | — | EP | disclosed |
| US-4372953-A | Tetrazole derivatives, and anti-ulcer composition containing the same | OTSUKA PHARMACEUTICAL COMPANY, LIMITED (JP) | 1983-02-08 | — | — | US | disclosed |
| EP-0035228-A1 | Tetrazole derivatives, process for the preparation thereof, and anti-ulcer composition containing the same | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1981-09-09 | — | — | EP | disclosed |