Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.51 |
| ▸ | RAB9A | P51151 | 4/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | PTPN11 | Q06124 | 3/20 | 0.49 |
| ▸ | THRB | P10828 | 2/20 | 0.48 |
| ▸ | THRA | P10827 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 4/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10979303 | 1.00 | MAPT (0.51) | MAPTRAB9AL3MBTL1ATMPTPN11 | |
| SCHEMBL10984612 | 1.00 | MAPT (0.51) | MAPTRAB9AL3MBTL1ATMPTPN11 | |
| SCHEMBL10984562 | 1.00 | MAPT (0.51) | MAPTRAB9AL3MBTL1ATMPTPN11 | |
| SCHEMBL10979314 | 1.00 | MAPT (0.51) | MAPTRAB9AL3MBTL1ATMPTPN11 | |
| SCHEMBL10979485 | 0.98 | MAPT (0.52) | MAPTRAB9AL3MBTL1ATMPTPN11 | |
| SCHEMBL10979533 | 0.94 | L3MBTL1 (0.54) | MAPTRAB9AL3MBTL1ATMALDH1A1 | |
| SCHEMBL9399929 | 0.92 | THRA (0.53) | MAPTRAB9AL3MBTL1ATMPTPN11 | |
| SCHEMBL9398890 | 0.92 | THRA (0.53) | MAPTRAB9AL3MBTL1ATMPTPN11 | |
| SCHEMBL10975067 | 0.89 | CSNK2A1 (0.55) | MAPTRAB9AL3MBTL1ATMALDH1A1 | |
| SCHEMBL12431879 | 0.87 | MAPT (0.65) | MAPTRAB9AL3MBTL1ATMTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0074608-B1 | LIQUID CRYSTAL HALOGEN COMPOUNDS, PROCESS FOR THEIR PREPARATION, DIELECTRIC AND DECTROOPTICAL DISPLAY ELEMENT CONTAINING THEM | MERCK PATENT GmbH (DE) | 1985-07-03 | — | — | EP | disclosed |
| US-4490305-A | Liquid-crystalline halogen compounds, process for their preparation, dielectrics containing these, and electro-optical display element | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1984-12-25 | — | — | US | disclosed |
| EP-0074608-A2 | Liquid crystal halogen compounds, process for their preparation, dielectric and dectrooptical display element containing them | MERCK PATENT GmbH (DE) | 1983-03-23 | — | — | EP | disclosed |