Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 12/20 | 0.49 |
| ▸ | BCHE | P06276 | 6/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | STAT3 | P40763 | 1/20 | 0.39 |
| ▸ | STAT1 | P42224 | 1/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.39 |
| ▸ | RELA | Q04206 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12043593 | 0.84 | ACHE (0.68) | ACHEBCHELMNAMEN1KMT2A | |
| SCHEMBL10815679 | 0.79 | ACHE (0.61) | ACHEBCHELMNAMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL21981144 | 0.78 | ACHE (0.51) | ACHEBCHELMNAMEN1KMT2A | |
| Metolcarb SCHEMBL11681132 | 0.74 | LMNA (0.62) | ACHEBCHELMNAKMT2AALDH1A1 | |
| Metolcarb SCHEMBL11000289 | 0.74 | LMNA (0.62) | ACHEBCHELMNAKMT2AALDH1A1 | |
| Metolcarb SCHEMBL29413999 | 0.73 | LMNA (0.65) | ACHEBCHELMNAKMT2AALDH1A1 | |
| SCHEMBL10971933 | 0.73 | CYP3A4 (0.65) | ACHEBCHELMNAALDH1A1KDM4E | |
| Metolcarb SCHEMBL118244 | 0.73 | LMNA (0.65) | ACHEBCHELMNAKMT2AALDH1A1 | |
| SCHEMBL20264521 | 0.73 | BCHE (0.55) | ACHEBCHELMNAMEN1KMT2A | |
| SCHEMBL11416323 | 0.72 | ACHE (0.48) | ACHEBCHELMNAALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0068294-B1 | A NEW ACARICIDAL COMPOSITION, PROCESSES FOR ITS PRODUCTION AND ITS USE | A. Nattermann & Cie. GmbH (DE) | 1985-12-18 | — | — | EP | claimed |
| EP-0068294-B1 | A NEW ACARICIDAL COMPOSITION, PROCESSES FOR ITS PRODUCTION AND ITS USE | A. Nattermann & Cie. GmbH (DE) | 1985-12-18 | — | — | EP | disclosed |