SCHEMBL29700271

SCHEMBL29700271

Clc1ccc(C(Cl)Cl)c(Cl)c1

nearest known ligand 0.58

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
TP53 P04637 3/20 0.58
LMNA P02545 1/20 0.58
HTT P42858 1/20 0.58
IDO1 P14902 2/20 0.44
TDO2 P48775 1/20 0.44
TSHR P16473 5/20 0.44
CYP3A4 P08684 4/20 0.44
HSD17B10 Q99714 2/20 0.44
TDP1 Q9NUW8 3/20 0.41
MAPK1 P28482 2/20 0.41
ALDH1A1 P00352 2/20 0.41
GAA P10253 1/20 0.41
ADRA2C P18825 1/20 0.39
CYP1A2 P05177 1/20 0.38
CYP2C9 P11712 1/20 0.38
CYP2C19 P33261 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7560420 1.00 TP53 (0.58) TP53LMNAHTTIDO1TDO2
SCHEMBL15440744 0.81 TP53 (0.60) TP53LMNAHTTIDO1TDO2
SCHEMBL9622386 0.81 TP53 (0.43) TP53LMNAHTTIDO1TDO2
SCHEMBL11267529 0.80 LMNA (0.54) TP53LMNAHTTIDO1TDO2
SCHEMBL13820253 0.80 TP53 (0.54) TP53LMNAHTTIDO1TDO2
SCHEMBL5108877 0.80 TP53 (0.65) TP53LMNAHTTIDO1TDO2
SCHEMBL30399939 0.80 TP53 (0.65) TP53LMNAHTTIDO1TDO2
SCHEMBL15053379 0.80 TP53 (0.65) TP53LMNAHTTIDO1TDO2
SCHEMBL7594119 0.79 TP53 (0.50) TP53LMNAHTTIDO1TSHR
SCHEMBL29700366 0.79 TP53 (0.50) TP53LMNAHTTIDO1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117342946-A Green treatment process for bis (2, 4-dichlorobenzoyl) peroxide mother liquor 江苏强盛功能化学股份有限公司 2024-01-05 CN claimed
CN-120005213-A Co-MOF (Co-metal organic framework) material, composite membrane material, preparation method and application 中原工学院 2025-05-16 CN disclosed
CN-113582836-B Method for synthesizing 2, 4-dichlorobenzoyl chloride 江苏聚由新材料科技有限公司 2024-12-03 CN disclosed
CN-118239861-A Preparation method of 1- (2, 4-dichlorophenyl) -1-cyclopropanecarbonitrile 山东京博农化科技股份有限公司 2024-06-25 CN disclosed
CN-113735680-B Synthesis method of 2, 4-dichlorobenzyl chloride 江苏聚由新材料科技有限公司 2024-06-18 CN disclosed
CN-117342946-A Green treatment process for bis (2, 4-dichlorobenzoyl) peroxide mother liquor 江苏强盛功能化学股份有限公司 2024-01-05 CN disclosed
CN-117342946-A Green treatment process for bis (2, 4-dichlorobenzoyl) peroxide mother liquor 江苏强盛功能化学股份有限公司 2024-01-05 CN disclosed
CN-116640056-A Synthesis and byproduct purification method of 2, 4-dichlorobenzoyl chloride 湖北联昌新材料有限公司 2023-08-25 CN disclosed
CN-115433069-A Preparation method of 2, 4-dichlorobenzaldehyde 柳州东风容泰化工股份有限公司 2022-12-06 CN disclosed
CN-109111463-B Method for producing aromatic compound DIC株式会社 2022-07-01 CN disclosed