Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | CYP26A1 | O43174 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10407564 | 0.80 | MAPT (0.55) | KMT2AMAPTHSP90AA1CYP3A4LMNA | |
| SCHEMBL12418531 | 0.78 | MAPT (0.58) | KMT2AMAPTHSP90AA1CYP3A4CYP1A2 | |
| SCHEMBL9023256 | 0.76 | MAPT (0.48) | KMT2AMAPTHSP90AA1CYP3A4CYP1A2 | |
| SCHEMBL10978264 | 0.76 | KMT2A (0.42) | KMT2AMAPTHSP90AA1MEN1 | |
| SCHEMBL11667101 | 0.73 | MAPT (0.43) | MAPTPPARG | |
| SCHEMBL10976959 | 0.72 | LCK (0.44) | MAPTPPARGL3MBTL1CNR1CNR2 | |
| SCHEMBL12415427 | 0.72 | MAPT (0.60) | KMT2AMAPTHSP90AA1CYP3A4CYP1A2 | |
| SCHEMBL11001173 | 0.71 | CYP3A4 (0.55) | KMT2AMAPTHSP90AA1CYP3A4CYP1A2 | |
| SCHEMBL1965569 | 0.70 | MAPT (0.53) | KMT2AMAPTHSP90AA1CYP3A4MEN1 | |
| SCHEMBL1923770 | 0.70 | MAPT (0.55) | KMT2AMAPTHSP90AA1CYP3A4CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0129798-A1 | Fungicidal azole compounds, their preparation and use | BASF Aktiengesellschaft (DE) | 1985-01-02 | — | — | EP | disclosed |