Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | SMO | Q99835 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
| ▸ | CYP26A1 | O43174 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9023287 | 0.90 | CYP3A4 (0.51) | MAPTKMT2AHSP90AA1CYP3A4CYP1A2 | |
| SCHEMBL9823725 | 0.80 | CYP3A4 (0.53) | MAPTKMT2AHSP90AA1CYP3A4CYP1A2 | |
| SCHEMBL12415427 | 0.78 | MAPT (0.60) | MAPTKMT2AHSP90AA1CYP3A4CYP1A2 | |
| SCHEMBL10745423 | 0.78 | MAPT (0.61) | MAPTKMT2AHSP90AA1CYP3A4CYP1A2 | |
| SCHEMBL10727541 | 0.77 | MAPT (0.79) | MAPTKMT2AHSP90AA1CYP3A4CYP1A2 | |
| SCHEMBL10976246 | 0.76 | KMT2A (0.45) | MAPTKMT2AHSP90AA1CYP3A4CYP1A2 | |
| SCHEMBL9389925 | 0.76 | MAPT (0.40) | MAPTKMT2AHSP90AA1CYP3A4CYP1A2 | |
| SCHEMBL9862847 | 0.75 | CYP3A4 (0.55) | MAPTKMT2AHSP90AA1CYP3A4CYP1A2 | |
| SCHEMBL9388155 | 0.73 | MAPT (0.44) | MAPTKMT2AHSP90AA1CYP3A4MEN1 | |
| SCHEMBL10765462 | 0.73 | MAPT (0.44) | MAPTKMT2AHSP90AA1CYP3A4MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0702676-A1 | CYCLOBUTYLAZOLES | BAYER AG (DE) | 1996-03-27 | — | — | EP | disclosed |
| WO-1994029281-A1 | CYCLOBUTYLAZOLES | BAYER AKTIENGESELLSCHAFT (DE) | 1994-12-22 | — | — | WO | disclosed |