Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 1/20 | 0.40 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.40 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.40 |
| ▸ | DUT | P33316 | 3/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31683796 | 0.98 | CYP4F2 (0.39) | CRBNCYP4F2CYP4A11DUT | |
| SCHEMBL28411762 | 0.94 | CRBN (0.41) | CRBNCYP4F2CYP4A11DUTEPHX2 | |
| SCHEMBL11257635 | 0.87 | CRBN (0.46) | CRBNCYP4F2CYP4A11DUTEPHX2 | |
| SCHEMBL4190795 | 0.87 | CRBN (0.46) | CRBNCYP4F2CYP4A11DUTEPHX2 | |
| SCHEMBL29125123 | 0.85 | CRBN (0.44) | CRBNCYP4F2CYP4A11EPHX2 | |
| SCHEMBL29125162 | 0.80 | CYP4F2 (0.43) | CRBNCYP4F2CYP4A11DUTEPHX2 | |
| SCHEMBL461664 | 0.80 | CRBN (0.45) | CRBNCYP4F2CYP4A11DUT | |
| SCHEMBL13179851 | 0.80 | CRBN (0.40) | CRBNCYP4F2CYP4A11DUTEPHX2 | |
| SCHEMBL4751061 | 0.80 | CRBN (0.40) | CRBNCYP4F2CYP4A11DUT | |
| SCHEMBL11531179 | 0.80 | CRBN (0.40) | CRBNCYP4F2CYP4A11DUTEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107216290-B | 3-butyl-5, 5-dimethyl hydantoin imidazole quaternary ammonium salt and preparation method thereof | 陕西科技大学 | 2021-03-16 | — | — | CN | claimed |
| CN-107216290-B | 3-butyl-5, 5-dimethyl hydantoin imidazole quaternary ammonium salt and preparation method thereof | 陕西科技大学 | 2021-03-16 | — | — | CN | disclosed |
| CN-106518771-A | 3-bromobutyl-5,5-dimethylhydantoin and preparation method thereof | 陕西科技大学 | 2017-03-22 | — | — | CN | disclosed |
| EP-0060610-B1 | HEXAHYDRO-TRANS- AND TETRAHYDROPYRIDOINDOLE NEUROLEPTIC AGENTS | PFIZER INC. (US) | 1985-09-04 | — | — | EP | disclosed |
| US-4432978-A | NEUROLEPTIC AGENTS, TRANQUILIZERS | PFIZER INC. (US) | 1984-02-21 | — | — | US | disclosed |
| US-4431649-A | TRANQUILIZERS | PFIZER INC. (US) | 1984-02-14 | — | — | US | disclosed |
| US-4431646-A | TRANQUILIZERS; PSYCHOSIS; NERVOUS SYSTEM DISORDERS | PFIZER INC. (US) | 1984-02-14 | — | — | US | disclosed |
| US-4427679-A | TRANQUILIZERS; PSYCHOLOGICAL DISORDERS | PFIZER INC. (US) | 1984-01-24 | — | — | US | disclosed |
| EP-0060610-A1 | Hexahydro-trans- and tetrahydropyridoindole neuroleptic agents | PFIZER INC. (US) | 1982-09-22 | — | — | EP | disclosed |
| US-4337250-A | NEUROLEPTIC AGENTS | PFIZER INC. (US) | 1982-06-29 | — | — | US | disclosed |
| US-4100285-A | VASODILATION | NIPPON SHINYAKU CO., LTD. (JP) | 1978-07-11 | — | — | US | disclosed |