SCHEMBL4190795

SCHEMBL4190795

O=C1CN(CCCCCN2CC(=O)NC2=O)C(=O)N1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CRBN Q96SW2 3/20 0.46
CYP4F2 P78329 1/20 0.43
CYP4A11 Q02928 1/20 0.43
DUT P33316 7/20 0.36
TOP2A P11388 2/20 0.33
TOP2B Q02880 2/20 0.33
ALDH1A1 P00352 2/20 0.33
MAPT P10636 2/20 0.33
TDP1 Q9NUW8 1/20 0.33
EPHX2 P34913 1/20 0.33
DDB1 Q16531 2/20 0.32
ALOX5 P09917 2/20 0.32
PTGS1 P23219 2/20 0.31
LMNA P02545 2/20 0.31
HSP90AA1 P07900 1/20 0.31
TLR9 Q9NR96 1/20 0.31
FAAH O00519 1/20 0.31
TP53 P04637 1/20 0.31
PKM P14618 1/20 0.31
HPGD P15428 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11257635 1.00 CRBN (0.46) CRBNCYP4F2CYP4A11DUTTOP2A
SCHEMBL6233785 0.90 ALOX5 (0.45) CRBNCYP4F2CYP4A11DUTALDH1A1
SCHEMBL31683796 0.90 CYP4F2 (0.39) CRBNCYP4F2CYP4A11DUT
SCHEMBL3628533 0.90 ALOX5 (0.45) CRBNCYP4F2CYP4A11DUTALDH1A1
SCHEMBL6228568 0.90 ALOX5 (0.45) CRBNCYP4F2CYP4A11DUTALDH1A1
SCHEMBL162839 0.90 ALOX5 (0.45) CRBNCYP4F2CYP4A11DUTALDH1A1
SCHEMBL20441211 0.90 ALOX5 (0.45) CRBNCYP4F2CYP4A11DUTALDH1A1
SCHEMBL8716131 0.90 ALOX5 (0.45) CRBNCYP4F2CYP4A11DUTALDH1A1
SCHEMBL6233217 0.90 ALOX5 (0.45) CRBNCYP4F2CYP4A11DUTALDH1A1
SCHEMBL20376257 0.90 ALOX5 (0.45) CRBNCYP4F2CYP4A11DUTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1674526-B9 POLYACETAL RESIN COMPOSITION POLYPLASTICS CO (JP) 2013-05-29 EP disclosed
EP-1674526-B1 POLYACETAL RESIN COMPOSITION POLYPLASTICS CO (JP) 2012-12-05 EP disclosed
EP-1679346-B1 POLYACETAL RESIN COMPOSITION POLYPLASTICS CO (JP) 2012-11-14 EP disclosed
US-7638565-B2 Polyacetal resin composition POLYPLASTICS CO., LTD. (JP) 2009-12-29 US disclosed
US-20090143506-A1 Aldehyde inhibitor composition and polyacetal resin composition POLYPLASTICS CO., LTD. (JP) 2009-06-04 US disclosed
US-20070123617-A1 Polyacetal resin composition DEUTSCHE BANK AG, NEW YORK BRANCH, AS COLLATERAL AGENT 2007-05-31 US disclosed
US-20070054998-A1 Polyacetal resin composition POLYPLASTICS CO., LTD. (JP) 2007-03-08 US disclosed
US-20070032605-A1 Polyacetal resin composition POLYPLASTICS CO., LTD. (JP) 2007-02-08 US disclosed
EP-1686156-A1 POLYACETAL RESIN COMPOSITION Polyplastics Co., Ltd. (JP) 2006-08-02 EP disclosed
EP-1683838-A1 ALDEHYDE INHIBITOR COMPOSITION AND POLYACETAL RESIN COMPOSITION Polyplastics Co., Ltd. (JP) 2006-07-26 EP disclosed
EP-1679346-A1 POLYACETAL RESIN COMPOSITION Polyplastics Co., Ltd. (JP) 2006-07-12 EP disclosed
EP-1674526-A1 POLYACETAL RESIN COMPOSITION Polyplastics Co., Ltd. (JP) 2006-06-28 EP disclosed