Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 1/20 | 0.45 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.42 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.40 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.40 |
| ▸ | GBA1 | P04062 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.38 |
| ▸ | MGLL | Q99685 | 3/20 | 0.38 |
| ▸ | FAAH | O00519 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | DUT | P33316 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL162839 | 0.98 | ALOX5 (0.45) | CRBNALOX5CYP4F2CYP4A11GBA1 | |
| SCHEMBL3628533 | 0.98 | ALOX5 (0.45) | CRBNALOX5CYP4F2CYP4A11GBA1 | |
| SCHEMBL20376257 | 0.98 | ALOX5 (0.45) | CRBNALOX5CYP4F2CYP4A11GBA1 | |
| SCHEMBL6228568 | 0.98 | ALOX5 (0.45) | CRBNALOX5CYP4F2CYP4A11GBA1 | |
| SCHEMBL6233217 | 0.98 | ALOX5 (0.45) | CRBNALOX5CYP4F2CYP4A11GBA1 | |
| SCHEMBL20441211 | 0.98 | ALOX5 (0.45) | CRBNALOX5CYP4F2CYP4A11GBA1 | |
| SCHEMBL8716131 | 0.98 | ALOX5 (0.45) | CRBNALOX5CYP4F2CYP4A11GBA1 | |
| SCHEMBL6233785 | 0.98 | ALOX5 (0.45) | CRBNALOX5CYP4F2CYP4A11GBA1 | |
| SCHEMBL194067 | 0.94 | CRBN (0.46) | CRBNALOX5CYP4F2CYP4A11GBA1 | |
| SCHEMBL4190795 | 0.87 | CRBN (0.46) | CRBNALOX5CYP4F2CYP4A11PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 189 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2419422-B1 | IMIDAZOLIDINE-2,4-DIONE DERIVATIVES AND USE THEREOF AS A MEDICAMENT | IPSEN PHARMA SAS (FR) | 2014-10-15 | — | — | EP | claimed |
| US-8624037-B2 | Imidazolidine-2,4-dione derivatives and use thereof as a medicament | IPSEN PHARMA S.A.S. (FR) | 2014-01-07 | — | — | US | claimed |
| US-20120095068-A1 | IMIDAZOLIDINE-2,4-DIONE DERIVATIVES AND USE THEREOF AS A MEDICAMENT | IPSEN PHARMA S.A.S. (FR) | 2012-04-19 | — | — | US | claimed |
| EP-1778827-A1 | STABLE NONAQUEOUS BLEACHING DETERGENT COMPOSITION DISPERSION | JohnsonDiversey, Inc., Renee J. Rymarz (US) | 2007-05-02 | — | — | EP | claimed |
| WO-2006014223-A1 | STABLE NONAQUEOUS BLEACHING DETERGENT COMPOSITION DISPERSION | JOHNSONDIVERSEY, INC. (US) | 2006-02-09 | — | — | WO | claimed |
| CN-1454042-A | Method for producing printing circuit board | SHEPLEY CO (US) | 2003-11-05 | — | — | CN | claimed |
| CN-1039283-C | Use of Porphyrins | FMC CORP (US) | 1998-07-29 | — | — | CN | claimed |
| US-5407808-A | Treating tumor with inhibitor of protoporphyrinogen conversion to heme | FMC CORPORATION (US) | 1995-04-18 | — | — | US | claimed |
| US-5298502-A | Exposure to light in presence of oxidase inhibitor | FMC CORPORATION (US) | 1994-03-29 | — | — | US | claimed |
| EP-0447491-B1 | PROTOPORPHYRINOGEN INHIBITORS AND THEIR USE IN COMPOSITIONS FOR DETECTING AND TREATING TUMOURS | FMC CORP (US) | 1993-08-11 | — | — | EP | claimed |
| WO-2023235480-A1 | ARYL HYDANTOIN COMPOUNDS AND METHODS OF USE | BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA (US) | 2023-12-07 | — | — | WO | disclosed |
| WO-2023235480-A1 | ARYL HYDANTOIN COMPOUNDS AND METHODS OF USE | BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA (US) | 2023-12-07 | — | — | WO | disclosed |
| US-20230135524-A1 | ARYL HYDANTOIN HETEROCYCLES AND METHODS OF USE | THE UNITED STATES OF AMERICA,AS REPRESENTED BY THE SECRETARY,DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2023-05-04 | — | — | US | disclosed |
| CN-113801064-A | Method for constructing phenylhydantoin by [3+2] cycloaddition reaction | 甘肃省化工研究院有限责任公司 | 2021-12-17 | — | — | CN | disclosed |
| CN-109796437-B | Hydantoin and thiohydantoin compounds with AR and HDAC dual inhibition effects and application | 上海健康医学院 | 2021-08-24 | — | — | CN | disclosed |
| EP-0011693-A1 | N-trifluoromethane-sulfonylaminophenyl-substituted N-heterocycles, their preparation, compositions containing them and their use in regulating plant growth | CIBA-GEIGY AG (CH) | 1980-06-11 | — | — | EP | disclosed |
| EP-0003861-A1 | Detergent bleach composition and process for removing stains from cotton fabrics | THE PROCTER & GAMBLE COMPANY (US) | 1979-09-05 | — | — | EP | disclosed |
| US-4003841-A | Coated stabilized bleach activators, process and washing compositions | HENKEL & CIE G.M.B.H. (DT) | 1977-01-18 | — | — | US | disclosed |
| US-3975280-A | Storage-stable, readily-soluble detergent additives, coating compositions and process | HENKEL & CIE G.M.B.H. (DT) | 1976-08-17 | — | — | US | disclosed |
| US-3780056-A | ACYL HYDANTOIN PHOSPHOROTHIOATES | SINGHAL G | 1973-12-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230135524-A1 | ARYL HYDANTOIN HETEROCYCLES AND METHODS OF USE | CYP21A2, AR, NR5A1 | CRBN 1178/4885ALOX5 3471/4885CYP4F2 236/4885 |
| US-20120095068-A1 | IMIDAZOLIDINE-2,4-DIONE DERIVATIVES AND USE THEREOF AS A MEDICAMENT | MKI67, CCNI, CCNA1 | CRBN 1729/4885ALOX5 3022/4885CYP4F2 1476/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.