Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.68 |
| ▸ | HSD17B10 | Q99714 | 7/20 | 0.68 |
| ▸ | TSHR | P16473 | 2/20 | 0.58 |
| ▸ | CDC25B | P30305 | 4/20 | 0.53 |
| ▸ | HPGD | P15428 | 6/20 | 0.50 |
| ▸ | RAB9A | P51151 | 5/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | CA7 | P43166 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2894636 | 0.90 | ALDH1A1 (0.72) | ALDH1A1HSD17B10TSHRCDC25BHPGD | |
| SCHEMBL11521675 | 0.88 | TSHR (0.68) | ALDH1A1HSD17B10TSHRCDC25BHPGD | |
| SCHEMBL10353071 | 0.85 | TSHR (0.63) | ALDH1A1HSD17B10TSHRCDC25BHPGD | |
| SCHEMBL7126414 | 0.84 | ALDH1A1 (0.60) | ALDH1A1HSD17B10TSHRCDC25BHPGD | |
| SCHEMBL7617766 | 0.83 | ALDH1A1 (0.58) | ALDH1A1HSD17B10TSHRCDC25BHPGD | |
| SCHEMBL1424504 | 0.83 | TSHR (0.61) | ALDH1A1HSD17B10TSHRCDC25BHPGD | |
| Ethyl Anthranilate SCHEMBL7560547 | 0.83 | ALDH1A1 (0.96) | ALDH1A1HSD17B10TSHRCDC25BHPGD | |
| Ethyl Anthranilate SCHEMBL27460908 | 0.82 | ALDH1A1 (0.87) | ALDH1A1HSD17B10TSHRCDC25BHPGD | |
| SCHEMBL1097855 | 0.82 | CA12 (0.71) | ALDH1A1HSD17B10TSHRCDC25BRAB9A | |
| SCHEMBL30216752 | 0.81 | ALDH1A1 (0.65) | ALDH1A1HSD17B10TSHRHPGDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 73 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109970568-B | Synthesis process of 3-amino dimethyl phthalate | 扬州工业职业技术学院 | 2022-09-02 | — | — | CN | claimed |
| CN-216172207-U | Hydrogenation reaction kettle for preparing 3-amino-dimethyl phthalate | 山东友帮生化科技有限公司 | 2022-04-05 | — | — | CN | claimed |
| CN-110483304-A | A kind of preparation method of 3- aminophthalic acid dimethyl ester | YANGZHOU POLYTECHNIC INST | 2019-11-22 | — | — | CN | claimed |
| CN-109970568-A | A kind of green synthesis process of 3- aminophthalic acid dimethyl ester | 扬州工业职业技术学院 | 2019-07-05 | — | — | CN | claimed |
| CN-104945406-A | Aza-phenalene-3-ketone derivative, preparation method thereof and application of aza-phenalene-3-ketone derivative as PARP inhibitor | SUZHOU KANGRUN PHARMACEUTICALS INC | 2015-09-30 | — | — | CN | claimed |
| CN-109970568-B | Synthesis process of 3-amino dimethyl phthalate | 扬州工业职业技术学院 | 2022-09-02 | — | — | CN | disclosed |
| CN-109970568-B | Synthesis process of 3-amino dimethyl phthalate | 扬州工业职业技术学院 | 2022-09-02 | — | — | CN | disclosed |
| CN-110746400-A | Androgen receptor targeted fluorescent probe and preparation method thereof | 郑州大学 | 2020-02-04 | — | — | CN | disclosed |
| CN-110483304-A | A kind of preparation method of 3- aminophthalic acid dimethyl ester | YANGZHOU POLYTECHNIC INST | 2019-11-22 | — | — | CN | disclosed |
| CN-110483304-A | A kind of preparation method of 3- aminophthalic acid dimethyl ester | YANGZHOU POLYTECHNIC INST | 2019-11-22 | — | — | CN | disclosed |
| CN-110483304-A | A kind of preparation method of 3- aminophthalic acid dimethyl ester | YANGZHOU POLYTECHNIC INST | 2019-11-22 | — | — | CN | disclosed |
| US-10385037-B2 | 4′-O-substituted isoindoline derivatives and compositions comprising and methods of using the same | CELGENE CORPORATION (US) | 2019-08-20 | — | — | US | disclosed |
| US-20060025597-A1 | Isoindole-imide compounds, compositions, and uses thereof | CELGENE CORPORATION | 2006-02-02 | — | — | US | disclosed |
| US-20060025457-A1 | Isoindoline compounds and methods of their use | AMGEN INC. | 2006-02-02 | — | — | US | disclosed |
| EP-1363900-A1 | ISOINDOLE-IMIDE COMPOUNDS AS TNF-INHIBITORS | CELGENE CORPORATION (US) | 2003-11-26 | — | — | EP | disclosed |
| US-20030096841-A1 | Isoindole-imide compounds, compositions, and uses thereof | CELGENE CORPORATION | 2003-05-22 | — | — | US | disclosed |
| US-20030045552-A1 | Isoindole-imide compounds, compositions, and uses thereof | CELGENE CORPORATION | 2003-03-06 | — | — | US | disclosed |
| WO-2002059106-A1 | ISOINDOLE-IMIDE COMPOUNDS, COMPOSITIONS, AND USES THEREOF | CELGENE CORPORATION (US) | 2002-08-01 | — | — | WO | disclosed |
| EP-0781767-B1 | Process for producing isatoic anhydrides | SUMITOMO CHEMICAL CO (JP) | 2001-09-05 | — | — | EP | disclosed |
| EP-0781767-A1 | Process for producing isatoic anhydrides | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-07-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030045552-A1 | Isoindole-imide compounds, compositions, and uses thereof | TNF, IKZF3, IKZF1 | ALDH1A1 2514/4885HSD17B10 3247/4885TSHR 1322/4885 |
| US-20060025597-A1 | Isoindole-imide compounds, compositions, and uses thereof | TNF, IKZF3, TNFRSF1A | ALDH1A1 2190/4885HSD17B10 3313/4885TSHR 1341/4885 |
| US-20030096841-A1 | Isoindole-imide compounds, compositions, and uses thereof | TNF, IKZF3, IKZF1 | ALDH1A1 2514/4885HSD17B10 3247/4885TSHR 1322/4885 |
| US-20060025457-A1 | Isoindoline compounds and methods of their use | PDE4A, PDE4B, PDE4C | ALDH1A1 293/4885HSD17B10 723/4885TSHR 4195/4885 |
| US-10385037-B2 | 4′-O-substituted isoindoline derivatives and compositions comprising and methods of using the same | CYP3A4, CYP3A7, CYP4B1 | ALDH1A1 1450/4885HSD17B10 1570/4885TSHR 4235/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.