Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | ELANE | P08246 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 5/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10975730 | 0.87 | ELANE (0.41) | L3MBTL1ALDH1A1ELANEMAPTKDM4E | |
| SCHEMBL10974689 | 0.86 | RAB9A (0.36) | L3MBTL1ALDH1A1ELANEMAPTKDM4E | |
| SCHEMBL10977617 | 0.68 | CNR1 (0.46) | ALDH1A1MAPTSMN1; SMN2RAB9AKMT2A | |
| SCHEMBL14900672 | 0.65 | PBRM1 (0.43) | ELANEKDM4ERAB9A | |
| SCHEMBL9386679 | 0.65 | ALDH1A1 (0.44) | L3MBTL1ALDH1A1MAPTKDM4ERAB9A | |
| SCHEMBL28268333 | 0.64 | TACR1 (0.46) | KDM4ESMN1; SMN2RAB9AMEN1KMT2A | |
| SCHEMBL30689222 | 0.64 | TOP2A (0.33) | L3MBTL1MAPTKDM4ESMN1; SMN2MAPK1 | |
| SCHEMBL20483536 | 0.64 | SMN1; SMN2 (0.36) | ALDH1A1KDM4ESMN1; SMN2RAB9A | |
| SCHEMBL9556162 | 0.63 | KDM4E (0.51) | ALDH1A1MAPTKDM4ESMN1; SMN2RAB9A | |
| SCHEMBL348854 | 0.63 | BRD4 (0.55) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0056637-B1 | 4(3H)-QUINAZOLINONE DERIVATIVES, PROCESS FOR PRODUCTION THEREOF AND PHARMACEUTICAL COMPOSITIONS COMPRISING SAID COMPOUNDS | Ishikawa, Masayuki (JP) | 1985-07-24 | — | — | EP | claimed |