SCHEMBL10977342

SCHEMBL10977342

Nc1ccc2cc(CCOS(=O)(=O)O)ccc2c1S(=O)(=O)S(=O)(=O)O

nearest known ligand 0.32

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
PTGS2 P35354 1/20 0.32
ALDH1A1 P00352 1/20 0.31
CYP2C9 P11712 1/20 0.31
CYP2C19 P33261 1/20 0.31
CASP6 P55212 1/20 0.31
HSD17B10 Q99714 1/20 0.31
CA1 P00915 2/20 0.31
CA2 P00918 2/20 0.31
CA9 Q16790 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10978163 0.75 NT5E (0.38) CASP6HSD17B10CA1CA2CA9
SCHEMBL5702855 0.71 ALDH1A1 (0.43) ALDH1A1CYP2C9CYP2C19CASP6HSD17B10
SCHEMBL9650734 0.70 ALDH1A1 (0.43) ALDH1A1CYP2C9CYP2C19CASP6HSD17B10
SCHEMBL9841095 0.70 ROCK1 (0.44) ALDH1A1CYP2C9CYP2C19CASP6HSD17B10
SCHEMBL10429484 0.69 CA1 (0.39) CA1CA2CA9
SCHEMBL10982417 0.68 NT5E (0.45) ALDH1A1CYP2C9CYP2C19CASP6HSD17B10
SCHEMBL9002486 0.68 RECQL (0.48) ALDH1A1CA1CA2CA9
SCHEMBL9133787 0.66 MAOB (0.50) ALDH1A1HSD17B10CA1CA2CA9
SCHEMBL9841088 0.66 ALDH1A1 (0.37) ALDH1A1CYP2C9CYP2C19CASP6HSD17B10
SCHEMBL11152201 0.66 ALDH1A1 (0.37) PTGS2ALDH1A1CYP2C9CYP2C19CASP6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4530996-A Containing naphthalene rings SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1985-07-23 US disclosed
EP-0068204-B1 REACTIVE MONO-FUNCTIONAL BISAZO BLUE-BLACK DYE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1985-04-24 EP disclosed
EP-0068204-A1 Reactive mono-functional bisazo blue-black dye SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1983-01-05 EP disclosed