SCHEMBL10429484

SCHEMBL10429484

Nc1ccc(CCOS(=O)(=O)O)cc1Br.O=[SH2]=O

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 7/20 0.39
CA2 P00918 7/20 0.39
CA9 Q16790 3/20 0.39
CA12 O43570 1/20 0.39
CA4 P22748 1/20 0.39
CA6 P23280 1/20 0.39
CA5A P35218 1/20 0.39
CA7 P43166 1/20 0.39
CA14 Q9ULX7 1/20 0.39
CA5B Q9Y2D0 1/20 0.39
SLC6A2 P23975 1/20 0.34
SLC6A4 P31645 1/20 0.34
SLC6A3 Q01959 1/20 0.34
KDM4E B2RXH2 1/20 0.32
MEN1 O00255 1/20 0.32
GAA P10253 1/20 0.32
MAPT P10636 1/20 0.32
PKM P14618 1/20 0.32
RAB9A P51151 1/20 0.32
KMT2A Q03164 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6935649 0.79 RECQL (0.44) CA1CA2CA9CA12CA6
SCHEMBL6937116 0.77 CA1 (0.46) CA1CA2CA9CA12CA4
SCHEMBL6885235 0.74 CA2 (0.53) CA1CA2CA9CA12CA4
SCHEMBL9002486 0.73 RECQL (0.48) CA1CA2CA9CA12CA6
Dimethylamine SCHEMBL17667849 0.72 CA12 (0.42) CA1CA2CA9CA12CA4
SCHEMBL9133787 0.71 MAOB (0.50) CA1CA2CA9CA12CA4
SCHEMBL11152201 0.70 ALDH1A1 (0.37) CA1CA2CA12CA4GAA
SCHEMBL20838237 0.70 APP (0.54) CA1CA2CA4CA6SLC6A2
SCHEMBL10977342 0.69 PTGS2 (0.32) CA1CA2CA9
SCHEMBL10692522 0.69 CA1 (0.47) CA1CA2CA9CA12CA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4935500-A Blue color SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1990-06-19 US disclosed