Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY1 | P47900 | 15/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.53 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10972225 | 0.92 | KDM4E (0.60) | P2RY1KDM4EMEN1CYP1A2CYP2C19 | |
| SCHEMBL29991644 | 0.83 | MEN1 (0.63) | P2RY1KDM4EMEN1CYP1A2CYP2C19 | |
| SCHEMBL2333429 | 0.83 | MEN1 (0.63) | P2RY1KDM4EMEN1CYP1A2CYP2C19 | |
| SCHEMBL30166677 | 0.83 | MEN1 (0.63) | P2RY1KDM4EMEN1CYP1A2CYP2C19 | |
| SCHEMBL30792433 | 0.81 | KMT2A (0.62) | P2RY1KDM4EMEN1CYP1A2CYP2C19 | |
| SCHEMBL9122123 | 0.80 | TDP1 (0.66) | P2RY1KDM4EMEN1CYP1A2CYP2C19 | |
| SCHEMBL8177633 | 0.79 | KDM4E (0.62) | P2RY1KDM4EMEN1CYP1A2CYP2C19 | |
| SCHEMBL10969027 | 0.79 | KDM4E (0.62) | P2RY1KDM4EMEN1CYP1A2CYP2C19 | |
| SCHEMBL4302001 | 0.79 | KMT2A (0.49) | KDM4EMEN1KMT2AGPBAR1RXFP1 | |
| O-Xylene SCHEMBL28789870 | 0.78 | KDM4E (0.56) | P2RY1KDM4EMEN1CYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0053011-A1 | New herbicidal nicotinamide derivatives | MAY & BAKER LIMITED (GB) | 1982-06-02 | — | — | EP | claimed |
| EP-0053011-B1 | NEW HERBICIDAL NICOTINAMIDE DERIVATIVES | MAY & BAKER LIMITED (GB) | 1985-04-03 | — | — | EP | disclosed |
| EP-0053011-A1 | New herbicidal nicotinamide derivatives | MAY & BAKER LIMITED (GB) | 1982-06-02 | — | — | EP | disclosed |