Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | DHODH | Q02127 | 1/20 | 0.41 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16487052 | 0.85 | KMT2A (0.53) | KMT2APOLBKDM4EALDH1A1L3MBTL1 | |
| SCHEMBL4307224 | 0.81 | POLB (0.51) | KMT2APOLBKDM4EALDH1A1NR1H3 | |
| SCHEMBL18816705 | 0.80 | POLB (0.54) | KMT2APOLBKDM4ENR1H3NR1H2 | |
| SCHEMBL10977484 | 0.79 | P2RY1 (0.55) | KMT2AKDM4EGPBAR1MEN1RXFP1 | |
| SCHEMBL2301749 | 0.78 | DHODH (0.57) | KMT2AKDM4EALDH1A1L3MBTL1LMNA | |
| SCHEMBL30087468 | 0.78 | DHODH (0.57) | KMT2AKDM4EALDH1A1L3MBTL1LMNA | |
| SCHEMBL12300200 | 0.76 | POLB (0.64) | KMT2APOLBKDM4EALDH1A1L3MBTL1 | |
| SCHEMBL3137908 | 0.75 | GPBAR1 (0.72) | KMT2APOLBKDM4EALDH1A1L3MBTL1 | |
| SCHEMBL11243535 | 0.75 | GPBAR1 (0.44) | KMT2APOLBKDM4EALDH1A1L3MBTL1 | |
| SCHEMBL27313359 | 0.74 | TDP1 (0.61) | POLBKDM4EALDH1A1L3MBTL1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090163471-A1 | Tropane compounds | EXELIXIS, INC. | 2009-06-25 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090163471-A1 | Tropane compounds | ADRA1B, ADRA2B, ADRB2 | KMT2A 3076/4885POLB 1234/4885KDM4E 4402/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.