Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.43 |
| ▸ | NOS1 | P29475 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | LTA4H | P09960 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | G6PC1 | P35575 | 1/20 | 0.41 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | CSF1R | P07333 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | OXTR | P30559 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10972930 | 0.86 | TP53 (0.47) | CYP19A1EGFRCSF1RNPC1RAB9A | |
| SCHEMBL10972922 | 0.84 | MCHR1 (0.43) | TRPM8EGFRNPC1RAB9AOXTR | |
| SCHEMBL10973834 | 0.80 | KDR (0.45) | LMNANPC1RAB9AL3MBTL1 | |
| SCHEMBL27827514 | 0.79 | LTA4H (0.55) | TSHRMAPK1LTA4HLMNAG6PC1 | |
| SCHEMBL10977769 | 0.79 | MERTK (0.46) | EGFRCSF1RNPC1RAB9A | |
| SCHEMBL8908075 | 0.77 | LTA4H (0.57) | TSHRLTA4HG6PC1TRPM8 | |
| SCHEMBL899366 | 0.77 | HSD17B2 (0.46) | TSHRNOS1MAPK1LMNASMN1; SMN2 | |
| SCHEMBL10971330 | 0.75 | KDR (0.41) | LMNATRPM8EGFRNPC1RAB9A | |
| SCHEMBL11876127 | 0.73 | BCHE (0.53) | TSHRLTA4HSMN1; SMN2NPC1RAB9A | |
| SCHEMBL6486634 | 0.73 | CYP2C19 (0.58) | TSHRCYP19A1MAPK1LTA4HLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-85103378-A | Process for preparing a group of novel compounds, formulations containing these compounds and their use in therapy | — | 1986-07-09 | — | — | CN | claimed |
| EP-0164204-A1 | Novel pharmaceutically useful pyrimidines | FISONS plc (GB) | 1985-12-11 | — | — | EP | claimed |