Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B2 | P37059 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.41 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.40 |
| ▸ | NOS1 | P29475 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.39 |
| ▸ | MMP9 | P14780 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.39 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | APP | P05067 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL899302 | 0.87 | CCNE1 (0.42) | HDAC1NPC1RAB9ALMNA | |
| SCHEMBL899508 | 0.86 | HDAC1 (0.47) | HDAC1ACKR3NPC1RAB9ALMNA | |
| SCHEMBL899084 | 0.84 | KCNH2 (0.38) | TSHRHDAC1ACKR3NPC1RAB9A | |
| SCHEMBL903025 | 0.82 | HDAC1 (0.40) | TSHRHDAC1 | |
| SCHEMBL902944 | 0.81 | HDAC1 (0.38) | HDAC1 | |
| SCHEMBL10977488 | 0.77 | TSHR (0.45) | TSHRNOS1NPC1RAB9AMAPK1 | |
| SCHEMBL10045592 | 0.76 | ALDH1A1 (0.39) | TSHRNPC1RAB9AMAPK1SMN1; SMN2 | |
| SCHEMBL27827514 | 0.75 | LTA4H (0.55) | TSHRNPC1RAB9AMAPK1LMNA | |
| SCHEMBL899484 | 0.74 | ALDH1A1 (0.38) | TSHRNPC1RAB9ALMNASMN1; SMN2 | |
| SCHEMBL899467 | 0.74 | ALDH1A1 (0.44) | ACKR3NPC1RAB9ALMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012040754-A2 | NOVEL THIAZOLAMINE DERIVATES AS DIFFERENTIATION ACCELERATORS | TECHNISCHE UNIVERSITÄT WIEN (AT) | 2012-04-05 | — | — | WO | disclosed |