Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | GHSR | Q92847 | 3/20 | 0.48 |
| ▸ | GPR84 | Q9NQS5 | 6/20 | 0.46 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.45 |
| ▸ | CTSV | O60911 | 1/20 | 0.44 |
| ▸ | CTSL | P07711 | 1/20 | 0.44 |
| ▸ | MGLL | Q99685 | 4/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.42 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10981744 | 1.00 | MTNR1A (0.49) | MTNR1AMEN1KMT2AATML3MBTL1 | |
| SCHEMBL10980290 | 1.00 | MTNR1A (0.49) | MTNR1AMEN1KMT2AATML3MBTL1 | |
| SCHEMBL14386721 | 1.00 | MTNR1A (0.49) | MTNR1AMEN1KMT2AATML3MBTL1 | |
| SCHEMBL10985402 | 1.00 | MTNR1A (0.49) | MTNR1AMEN1KMT2AATML3MBTL1 | |
| SCHEMBL10983064 | 1.00 | MTNR1A (0.49) | MTNR1AMEN1KMT2AATML3MBTL1 | |
| SCHEMBL7411185 | 0.95 | L3MBTL1 (0.51) | MTNR1AMEN1KMT2AATML3MBTL1 | |
| SCHEMBL10982423 | 0.90 | MEN1 (0.46) | MTNR1AMEN1KMT2AATML3MBTL1 | |
| SCHEMBL10983062 | 0.90 | MEN1 (0.46) | MTNR1AMEN1KMT2AATML3MBTL1 | |
| SCHEMBL10984403 | 0.90 | MEN1 (0.46) | MTNR1AMEN1KMT2AATML3MBTL1 | |
| SCHEMBL5882041 | 0.89 | MEN1 (0.56) | MTNR1AMEN1KMT2AATML3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4493843-A | Indole and indoline carboxylic acid compounds and method of use | MAY & BAKER LIMITED (GB) | 1985-01-15 | — | — | US | disclosed |
| EP-0042298-B1 | INDOLE AND INDOLINE DERIVATIVES | MAY & BAKER LIMITED (GB) | 1984-09-12 | — | — | EP | disclosed |
| EP-0042298-A1 | Indole and indoline derivatives | MAY & BAKER LIMITED (GB) | 1981-12-23 | — | — | EP | disclosed |