Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 5/20 | 0.38 |
| ▸ | PDGFRA | P16234 | 2/20 | 0.38 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.38 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.38 |
| ▸ | PAK4 | O96013 | 1/20 | 0.38 |
| ▸ | LTK | P29376 | 1/20 | 0.38 |
| ▸ | MAP2K2 | P36507 | 1/20 | 0.38 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.38 |
| ▸ | CDK8 | P49336 | 1/20 | 0.38 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.38 |
| ▸ | PRKX | P51817 | 1/20 | 0.38 |
| ▸ | NEK2 | P51955 | 1/20 | 0.38 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.38 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30517179 | 0.85 | HPGD (0.50) | HPGDHTTSMN1; SMN2NPC1RAB9A | |
| SCHEMBL29108035 | 0.85 | HPGD (0.50) | HPGDHTTSMN1; SMN2NPC1RAB9A | |
| SCHEMBL30517180 | 0.85 | HPGD (0.50) | HPGDHTTSMN1; SMN2NPC1RAB9A | |
| SCHEMBL11193963 | 0.85 | MAPT (0.50) | HPGDHTTSMN1; SMN2NPC1RAB9A | |
| SCHEMBL10942868 | 0.78 | HTT (0.47) | HPGDHTTSMN1; SMN2NPC1RAB9A | |
| SCHEMBL11253697 | 0.76 | PIK3CG (0.50) | HPGDSMN1; SMN2MAPTPDGFRACHEK1 | |
| SCHEMBL11283138 | 0.76 | HRH4 (0.48) | HPGDHTTSMN1; SMN2NPC1RAB9A | |
| SCHEMBL30665751 | 0.75 | BCHE (0.63) | HPGDSMN1; SMN2NPC1RAB9AMAPT | |
| SCHEMBL27323740 | 0.75 | BCHE (0.63) | HPGDSMN1; SMN2NPC1RAB9AMAPT | |
| SCHEMBL29108036 | 0.74 | HRH4 (0.43) | HPGDHTTSMN1; SMN2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0023785-B1 | QUINOXALINYLOXYPHENOXYALKANE CARBOXYLIC ACID DERIVATIVES, THEIR PREPARATION AND THEIR USE AS HERBICIDES | ICI AUSTRALIA LIMITED (AU) | 1985-04-03 | — | — | EP | disclosed |
| EP-0023785-A2 | Quinoxalinyloxyphenoxyalkane carboxylic acid derivatives, their preparation and their use as herbicides | ICI AUSTRALIA LIMITED (AU) | 1981-02-11 | — | — | EP | disclosed |