SCHEMBL27323740

SCHEMBL27323740

Oc1ccc(-c2cnc3cc(Cl)ccc3n2)cc1

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BCHE P06276 1/20 0.63
SMN1; SMN2 Q16637 2/20 0.58
NPC1 O15118 1/20 0.58
RAB9A P51151 1/20 0.58
MAPK1 P28482 1/20 0.53
RIPK1 Q13546 1/20 0.53
MEN1 O00255 3/20 0.51
MAPT P10636 3/20 0.51
KMT2A Q03164 3/20 0.51
ESR1 P03372 4/20 0.50
ESR2 Q92731 4/20 0.50
ESRRB O95718 2/20 0.50
ESRRA P11474 2/20 0.50
FGFR3 P22607 1/20 0.50
KDR P35968 1/20 0.50
TLR9 Q9NR96 1/20 0.46
HPGD P15428 2/20 0.45
ALDH1A1 P00352 2/20 0.44
GFER P55789 1/20 0.44
ADORA3 P0DMS8 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30665751 1.00 BCHE (0.63) BCHESMN1; SMN2NPC1RAB9AMAPK1
SCHEMBL30107670 0.92 NPC1 (0.68) BCHESMN1; SMN2NPC1RAB9AMAPT
SCHEMBL15850502 0.92 NPC1 (0.68) BCHESMN1; SMN2NPC1RAB9AMAPT
SCHEMBL25045587 0.88 NPC1 (0.55) BCHESMN1; SMN2NPC1RAB9AMAPK1
SCHEMBL30965461 0.88 NPC1 (0.55) BCHESMN1; SMN2NPC1RAB9AMAPK1
SCHEMBL28852479 0.86 BCHE (0.71) BCHESMN1; SMN2NPC1RAB9AMAPK1
SCHEMBL30965473 0.85 ALOX5 (0.53) BCHESMN1; SMN2NPC1RAB9AFGFR3
SCHEMBL25045580 0.85 ALOX5 (0.53) BCHESMN1; SMN2NPC1RAB9AFGFR3
SCHEMBL10555895 0.84 NPC1 (0.51) BCHESMN1; SMN2NPC1RAB9AMAPK1
SCHEMBL21777625 0.84 NPC1 (0.68) BCHESMN1; SMN2NPC1RAB9AMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103864703-A Method for preparing 6-chloro-2-quinoxaline phenol through catalytic hydrogenation of raney nickel Jiangsu fengshan group co ltd 2014-06-18 CN claimed
CN-102584722-A Efficient and environmentally-friendly method for preparing 6-chloro-2-quinoxaline phenol Jiangsu fengshan group co ltd 2012-07-18 CN claimed
CN-117069665-A Simple method for reducing sulfur residue in 2-hydroxy-6-chloroquinoxaline 山东京博生物科技有限公司 2023-11-17 CN disclosed
CN-103864703-B A kind of raney ni catalysis hydrogenation prepares the method for the chloro-2-quinoxaline phenol of 6- JIANGSU FENGSHAN GROUP CO., LTD. (CN) 2016-06-01 CN disclosed
CN-103864703-A Method for preparing 6-chloro-2-quinoxaline phenol through catalytic hydrogenation of raney nickel Jiangsu fengshan group co ltd 2014-06-18 CN disclosed
CN-103864703-A Method for preparing 6-chloro-2-quinoxaline phenol through catalytic hydrogenation of raney nickel Jiangsu fengshan group co ltd 2014-06-18 CN disclosed
CN-103864703-A Method for preparing 6-chloro-2-quinoxaline phenol through catalytic hydrogenation of raney nickel Jiangsu fengshan group co ltd 2014-06-18 CN disclosed
CN-102584722-A Efficient and environmentally-friendly method for preparing 6-chloro-2-quinoxaline phenol Jiangsu fengshan group co ltd 2012-07-18 CN disclosed
CN-102584722-A Efficient and environmentally-friendly method for preparing 6-chloro-2-quinoxaline phenol Jiangsu fengshan group co ltd 2012-07-18 CN disclosed
CN-102584722-A Efficient and environmentally-friendly method for preparing 6-chloro-2-quinoxaline phenol Jiangsu fengshan group co ltd 2012-07-18 CN disclosed
CN-1647639-A Composition for preventing straw-berry weeds and its preparing method and use SHANGHAI CITY PESTICIDE RES IN (CN) 2005-08-03 CN disclosed
CN-1051078-C Pyrazolinyl compounds for preventing crop from detriment of herbicides HOECHST AG (DE) 2000-04-05 CN disclosed
CN-1052115-A The pyrazoline compounds of protection preventing crop from detriment of herbicides HOECHST AG (DE) 1991-06-12 CN disclosed