Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.42 |
| ▸ | PDE7A | Q13946 | 3/20 | 0.40 |
| ▸ | PDE7B | Q9NP56 | 1/20 | 0.40 |
| ▸ | APP | P05067 | 1/20 | 0.40 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29108035 | 0.85 | HPGD (0.50) | MAPTHPGDHTTNPC1RAB9A | |
| SCHEMBL30517180 | 0.85 | HPGD (0.50) | MAPTHPGDHTTNPC1RAB9A | |
| SCHEMBL30517179 | 0.85 | HPGD (0.50) | MAPTHPGDHTTNPC1RAB9A | |
| SCHEMBL10978029 | 0.85 | HPGD (0.49) | MAPTHPGDHTTNPC1RAB9A | |
| SCHEMBL8559644 | 0.78 | MAPT (0.53) | MAPTHPGDSMN1; SMN2PIK3CGPDE7A | |
| SCHEMBL11283138 | 0.76 | HRH4 (0.48) | MAPTHPGDHTTNPC1RAB9A | |
| SCHEMBL29108036 | 0.74 | HRH4 (0.43) | MAPTHPGDHTTNPC1RAB9A | |
| SCHEMBL21793706 | 0.74 | TLR9 (0.60) | HPGDNPC1RAB9ASMN1; SMN2PIK3CG | |
| SCHEMBL4725394 | 0.73 | PIK3CG (0.53) | MAPTPIK3CGHRH4MAPK1 | |
| SCHEMBL24270323 | 0.72 | CYP3A4 (0.59) | MAPTHPGDHTTNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4376202-A | CHEMICAL INTERMEDIATES FOR INSECTICIDES | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 1983-03-08 | — | — | US | disclosed |