SCHEMBL109788

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL27776965	0.85	TAAR1 (0.53)	ESR1ESR2TAAR1SLC6A2ADRB2
	SCHEMBL110013	0.83	TRPA1 (0.56)	TAAR1SLC6A2CYP2D6SLC6A4SLC6A3
	SCHEMBL109099	0.82	TAAR1 (0.55)	ESR1ESR2TAAR1SLC6A2ADRB2
	SCHEMBL7526486	0.82	TAAR1 (0.59)	ESR1ESR2TAAR1SLC6A2ADRB2
	SCHEMBL443017	0.82	TAAR1 (0.59)	ESR1ESR2TAAR1SLC6A2ADRB2
	SCHEMBL106892	0.82	ESR1 (0.59)	ESR1ESR2TAAR1SLC6A2ADRB2
	SCHEMBL13165991	0.82	TAAR1 (0.59)	ESR1ESR2TAAR1SLC6A2ADRB2
	SCHEMBL7166607	0.77	TAAR1 (0.56)	ESR1ESR2TAAR1SLC6A2CYP3A4
	SCHEMBL8687796	0.77	TAAR1 (0.53)	ESR1ESR2TAAR1SLC6A2ADRB2
	SCHEMBL7084861	0.77	TAAR1 (0.53)	ESR1ESR2TAAR1SLC6A2ADRB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 111 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.