Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA7 | P43166 | 1/20 | 0.46 |
| ▸ | CTSL | P07711 | 2/20 | 0.44 |
| ▸ | CTSS | P25774 | 2/20 | 0.44 |
| ▸ | CTSK | P43235 | 2/20 | 0.44 |
| ▸ | CTSB | P07858 | 1/20 | 0.44 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.37 |
| ▸ | REN | P00797 | 2/20 | 0.37 |
| ▸ | APP | P05067 | 1/20 | 0.37 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.37 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.37 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.37 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.37 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.37 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3374209 | 0.88 | CA1 (0.44) | CA1CA2CA7CTSLCTSS | |
| SCHEMBL13413134 | 0.86 | CA1 (0.45) | CA1CA2CA7CTSLCTSS | |
| SCHEMBL13044120 | 0.86 | CA1 (0.45) | CA1CA2CA7CTSLCTSS | |
| SCHEMBL2760872 | 0.86 | CA1 (0.45) | CA1CA2CA7CTSLCTSS | |
| SCHEMBL9675593 | 0.84 | CA1 (0.46) | CA1CA2CA7CTSLCTSS | |
| SCHEMBL9676521 | 0.84 | CA1 (0.46) | CA1CA2CA7CTSLCTSS | |
| SCHEMBL13413131 | 0.84 | CA1 (0.45) | CA1CA2CA7CTSLCTSS | |
| SCHEMBL7445228 | 0.82 | CA1 (0.44) | CA1CA2CA7CTSLCTSS | |
| SCHEMBL14493059 | 0.82 | CYP2D6 (0.50) | CA1CA2CA7CTSLCTSS | |
| SCHEMBL2499493 | 0.82 | CYP2D6 (0.50) | CA1CA2CA7CTSLCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4548926-A | RENIN INHIBITOR | SANKYO COMPANY LIMITED (JP) | 1985-10-22 | — | — | US | disclosed |
| EP-0128762-A2 | New hypotensive peptides, their preparation and their use | SANKYO COMPANY LIMITED (JP) | 1984-12-19 | — | — | EP | disclosed |