Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA7 | P43166 | 1/20 | 0.46 |
| ▸ | CTSK | P43235 | 3/20 | 0.39 |
| ▸ | CTSL | P07711 | 2/20 | 0.39 |
| ▸ | CTSS | P25774 | 2/20 | 0.39 |
| ▸ | CTSB | P07858 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9676521 | 1.00 | CA1 (0.46) | CA1CA2CA7CTSKCTSL | |
| SCHEMBL7445228 | 0.89 | CA1 (0.44) | CA1CA2CA7CTSKCTSL | |
| SCHEMBL13044120 | 0.88 | CA1 (0.45) | CA1CA2CA7CTSKCTSL | |
| SCHEMBL2760872 | 0.88 | CA1 (0.45) | CA1CA2CA7CTSKCTSL | |
| SCHEMBL13413134 | 0.88 | CA1 (0.45) | CA1CA2CA7CTSKCTSL | |
| SCHEMBL10358181 | 0.87 | CA1 (0.42) | CA1CA2CA7CTSKCTSL | |
| SCHEMBL10866353 | 0.86 | REN (0.43) | CA1CA2CA7CTSKCTSS | |
| SCHEMBL9676607 | 0.86 | REN (0.43) | CA1CA2CA7CTSKCTSS | |
| SCHEMBL9677769 | 0.86 | REN (0.43) | CA1CA2CA7CTSKCTSS | |
| SCHEMBL9551921 | 0.86 | REN (0.43) | CA1CA2CA7CTSKCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0486478-A2 | Renin-inhibiting peptides | THE UPJOHN COMPANY (US) | 1992-05-20 | — | — | EP | disclosed |
| US-4885025-A | A PHENOXY-,-AMINO-,-ALKYLAMINO- OR -SULFIDO-SUBSTITUTED PHENYL ON THE NUMBER 1 RING NITROGEN | FMC CORPORATION (US) | 1989-12-05 | — | — | US | disclosed |
| US-4880781-A | HYPOTENSIVE AGENTS | THE UPJOHN COMPANY (US) | 1989-11-14 | — | — | US | disclosed |
| EP-0173481-A2 | Peptides | THE UPJOHN COMPANY (US) | 1986-03-05 | — | — | EP | disclosed |