Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | CTSL | P07711 | 2/20 | 0.38 |
| ▸ | CTSS | P25774 | 2/20 | 0.38 |
| ▸ | CTSK | P43235 | 2/20 | 0.38 |
| ▸ | CTSB | P07858 | 1/20 | 0.38 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.34 |
| ▸ | MMP2 | P08253 | 4/20 | 0.34 |
| ▸ | MMP1 | P03956 | 3/20 | 0.34 |
| ▸ | MMP3 | P08254 | 3/20 | 0.34 |
| ▸ | MMP9 | P14780 | 3/20 | 0.34 |
| ▸ | MMP8 | P22894 | 3/20 | 0.34 |
| ▸ | MMP13 | P45452 | 2/20 | 0.34 |
| ▸ | ADAM17 | P78536 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | MMP7 | P09237 | 2/20 | 0.33 |
| ▸ | MMP20 | O60882 | 1/20 | 0.33 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.33 |
| ▸ | TNF | P01375 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10358181 | 0.89 | CA1 (0.42) | CA1CA2CA7CTSLCTSS | |
| SCHEMBL9676521 | 0.89 | CA1 (0.46) | CA1CA2CA7CTSLCTSS | |
| SCHEMBL9675593 | 0.89 | CA1 (0.46) | CA1CA2CA7CTSLCTSS | |
| SCHEMBL7438624 | 0.86 | CA1 (0.40) | CA1CA2CA7CTSLCTSS | |
| SCHEMBL7443255 | 0.86 | CA1 (0.39) | CA1CA2CA7CTSLCTSS | |
| SCHEMBL7430597 | 0.84 | REN (0.45) | CA1CA2CA7CTSSCTSK | |
| SCHEMBL10866353 | 0.84 | REN (0.43) | CA1CA2CA7CTSSCTSK | |
| SCHEMBL9676607 | 0.84 | REN (0.43) | CA1CA2CA7CTSSCTSK | |
| SCHEMBL9677769 | 0.84 | REN (0.43) | CA1CA2CA7CTSSCTSK | |
| SCHEMBL9551921 | 0.84 | REN (0.43) | CA1CA2CA7CTSSCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0364493-A1 | RENIN INHIBITING PEPTIDES WITH NONPEPTIDE LINKAGES | THE UPJOHN COMPANY (US) | 1990-04-25 | — | — | EP | disclosed |
| WO-1989001488-A1 | RENIN INHIBITING PEPTIDES WITH NONPEPTIDE LINKAGES | THE UPJOHN COMPANY (US) | 1989-02-23 | — | — | WO | disclosed |