Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 2/20 | 0.54 |
| ▸ | ECE1 | P42892 | 2/20 | 0.54 |
| ▸ | CAPN1 | P07384 | 2/20 | 0.52 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.52 |
| ▸ | REN | P00797 | 3/20 | 0.51 |
| ▸ | CTSL | P07711 | 2/20 | 0.50 |
| ▸ | MMP3 | P08254 | 1/20 | 0.50 |
| ▸ | CTSB | P07858 | 1/20 | 0.50 |
| ▸ | HTRA1 | Q92743 | 1/20 | 0.49 |
| ▸ | CTSK | P43235 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10977845 | 1.00 | MME (0.54) | MMEECE1CAPN1ACE2REN | |
| SCHEMBL10978338 | 0.90 | MME (0.48) | MMEECE1CAPN1ACE2REN | |
| SCHEMBL7274809 | 0.89 | CAPN1 (0.60) | MMEECE1CAPN1CTSLCTSB | |
| SCHEMBL10636524 | 0.87 | CTSK (0.54) | CAPN1RENCTSLCTSBHTRA1 | |
| SCHEMBL10636541 | 0.86 | CTSL (0.59) | CAPN1CTSLCTSB | |
| SCHEMBL7938093 | 0.85 | CAPN1 (0.60) | CAPN1CTSLCTSBCTSK | |
| SCHEMBL9666956 | 0.85 | CTSL (0.54) | CAPN1CTSLCTSBCTSK | |
| SCHEMBL9551368 | 0.85 | CTSL (0.54) | CAPN1CTSLCTSBCTSK | |
| SCHEMBL27343932 | 0.85 | CTSL (0.54) | CAPN1CTSLCTSBCTSK | |
| SCHEMBL9551274 | 0.85 | CTSL (0.54) | CAPN1CTSLCTSBCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4548926-A | RENIN INHIBITOR | SANKYO COMPANY LIMITED (JP) | 1985-10-22 | — | — | US | disclosed |
| EP-0128762-A2 | New hypotensive peptides, their preparation and their use | SANKYO COMPANY LIMITED (JP) | 1984-12-19 | — | — | EP | disclosed |