Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A7 | Q99884 | 1/20 | 0.35 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.35 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | GOT1 | P17174 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7787172 | 0.76 | PLD1 (0.46) | TP53 | |
| SCHEMBL18920853 | 0.70 | SLC6A7 (0.41) | SLC6A7RIPK1TRPV1GOT1 | |
| SCHEMBL2001725 | 0.69 | SLC6A7 (0.47) | SLC6A7RIPK1TRPV1 | |
| SCHEMBL12607645 | 0.68 | SLC6A7 (0.49) | SLC6A7RIPK1TRPV1 | |
| SCHEMBL31005942 | 0.68 | SLC6A7 (0.49) | SLC6A7RIPK1TRPV1 | |
| SCHEMBL1834829 | 0.67 | CYP1A2 (0.50) | SLC6A7RIPK1TRPV1 | |
| SCHEMBL11401374 | 0.66 | TP53 (0.47) | TP53 | |
| SCHEMBL44773 | 0.66 | TP53 (0.48) | TP53 | |
| SCHEMBL2000100 | 0.66 | HTR3E (0.54) | SLC6A7RIPK1TRPV1 | |
| SCHEMBL27739674 | 0.66 | PLD1 (0.36) | SLC6A7TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4503056-A | ANTIINFLAMMATORY AGENTS | ABBOTT LABORATORIES (US) | 1985-03-05 | — | — | US | disclosed |