SCHEMBL10979490

SCHEMBL10979490

CCCN(CCC)c1ccc(/C=C2/CC(CC)C/C(=C\c3ccc(N(CCC)CCC)cc3)C2=O)cc1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 6/20 0.51
LMNA P02545 5/20 0.51
ALDH1A1 P00352 4/20 0.51
HTT P42858 3/20 0.51
RAB9A P51151 3/20 0.51
HSP90AA1 P07900 2/20 0.51
SMN1; SMN2 Q16637 2/20 0.51
MEN1 O00255 4/20 0.47
KMT2A Q03164 4/20 0.47
L3MBTL1 Q9Y468 2/20 0.47
POLB P06746 1/20 0.47
RECQL P46063 1/20 0.47
CYP1A2 P05177 1/20 0.42
ACHE P22303 1/20 0.42
STAT3 P40763 1/20 0.40
NSD2 O96028 1/20 0.40
DRD3 P35462 1/20 0.39
NPC1 O15118 2/20 0.39
MAPK1 P28482 2/20 0.39
MCOLN3 Q8TDD5 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10977686 1.00 MAPT (0.51) MAPTLMNAALDH1A1HTTRAB9A
SCHEMBL10976308 0.90 CYP1A2 (0.41) MAPTLMNAALDH1A1HTTRAB9A
SCHEMBL10976305 0.90 CYP1A2 (0.41) MAPTLMNAALDH1A1HTTRAB9A
SCHEMBL10979150 0.89 ALDH1A1 (0.53) MAPTLMNAALDH1A1HTTRAB9A
SCHEMBL10979146 0.89 ALDH1A1 (0.53) MAPTLMNAALDH1A1HTTRAB9A
SCHEMBL10977916 0.87 MAPT (0.54) MAPTLMNAALDH1A1HTTRAB9A
SCHEMBL10977914 0.87 MAPT (0.54) MAPTLMNAALDH1A1HTTRAB9A
SCHEMBL10974381 0.84 CYP1A2 (0.60) MAPTLMNAALDH1A1HTTRAB9A
SCHEMBL10974383 0.84 CYP1A2 (0.60) MAPTLMNAALDH1A1HTTRAB9A
SCHEMBL10980442 0.81 CYP1A2 (0.65) MAPTLMNAALDH1A1HTTRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0068808-B1 PHOTORESIST COMPOSITION JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1985-06-05 EP claimed
EP-0068808-A2 Photoresist composition JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1983-01-05 EP claimed
EP-0068808-B1 PHOTORESIST COMPOSITION JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1985-06-05 EP disclosed
EP-0068808-A2 Photoresist composition JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1983-01-05 EP disclosed