SCHEMBL10979660

SCHEMBL10979660

OCCC1CC2C=CC1CC2

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.30
ALDH1A1 P00352 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17934495 0.83 KDM4E (0.43) KDM4EALDH1A1
SCHEMBL5833567 0.83 KDM4E (0.32) KDM4EALDH1A1
SCHEMBL31110008 0.83 KDM4E (0.32) KDM4EALDH1A1
SCHEMBL15923553 0.83 KDM4E (0.43) KDM4EALDH1A1
SCHEMBL146208 0.83 KDM4E (0.43) KDM4EALDH1A1
SCHEMBL20216346 0.79 KDM4E (0.37) KDM4EALDH1A1
SCHEMBL11611838 0.77 TDP1 (0.36) KDM4EALDH1A1
SCHEMBL11614552 0.74 ALOX5 (0.44) KDM4EALDH1A1
SCHEMBL20216336 0.74 KDM4E (0.39) KDM4EALDH1A1
SCHEMBL7718211 0.74 KDM4E (0.32) KDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4543428-A Production of a hexahydronaphthalenone compound OREGON GRADUATE CENTER FOR STUDY & RESEARCH (US) 1985-09-24 US claimed
US-4515720-A Method of synthesizing a late-stage intermediate to 11-deoxydaunorubicin and 11-deoxyadriamycin, and two precursors to the object intermediate OREGON GRADUATE CENTER FOR STUDY & RESEARCH (US) 1985-05-07 US claimed
US-4543428-A Production of a hexahydronaphthalenone compound OREGON GRADUATE CENTER FOR STUDY & RESEARCH (US) 1985-09-24 US disclosed
US-4543428-A Production of a hexahydronaphthalenone compound OREGON GRADUATE CENTER FOR STUDY & RESEARCH (US) 1985-09-24 US disclosed
US-4515720-A Method of synthesizing a late-stage intermediate to 11-deoxydaunorubicin and 11-deoxyadriamycin, and two precursors to the object intermediate OREGON GRADUATE CENTER FOR STUDY & RESEARCH (US) 1985-05-07 US disclosed
US-4515720-A Method of synthesizing a late-stage intermediate to 11-deoxydaunorubicin and 11-deoxyadriamycin, and two precursors to the object intermediate OREGON GRADUATE CENTER FOR STUDY & RESEARCH (US) 1985-05-07 US disclosed