SCHEMBL146208

SCHEMBL146208

OCCC1CC2C=CC1C2

nearest known ligand 0.45

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 12/20 0.43
ALDH1A1 P00352 4/20 0.43
TSHR P16473 1/20 0.38
TDP1 Q9NUW8 4/20 0.36
LMNA P02545 1/20 0.35
MEN1 O00255 2/20 0.35
KMT2A Q03164 2/20 0.35
HTT P42858 1/20 0.35
GAA P10253 1/20 0.34
EPHX2 P34913 2/20 0.33
POLB P06746 1/20 0.33
ALOX15 P16050 1/20 0.33
PKM P14618 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17934495 1.00 KDM4E (0.43) KDM4EALDH1A1TSHRTDP1LMNA
SCHEMBL15923553 1.00 KDM4E (0.43) KDM4EALDH1A1TSHRTDP1LMNA
SCHEMBL2979672 0.87 KDM4E (0.41) KDM4EALDH1A1TSHRTDP1LMNA
SCHEMBL1012047 0.85 KDM4E (0.48) KDM4EALDH1A1TSHRTDP1LMNA
SCHEMBL2513013 0.85 KDM4E (0.40) KDM4EALDH1A1TSHRTDP1LMNA
SCHEMBL13346630 0.84 KDM4E (0.39) KDM4EALDH1A1TSHRTDP1LMNA
SCHEMBL13346629 0.84 KDM4E (0.39) KDM4EALDH1A1TSHRTDP1LMNA
SCHEMBL13346627 0.84 KDM4E (0.39) KDM4EALDH1A1TSHRTDP1LMNA
SCHEMBL13346631 0.84 KDM4E (0.39) KDM4EALDH1A1TSHRTDP1LMNA
SCHEMBL5604286 0.84 KDM4E (0.39) KDM4EALDH1A1TSHRTDP1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 544 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112679642-B Cycloolefin copolymer and preparation method thereof 广东华锦达新材科技有限公司 2023-05-12 CN claimed
CN-113372478-B Aldehyde group functionalized cycloolefin-ethylene copolymer and preparation method thereof 万华化学集团股份有限公司 2022-07-15 CN claimed
CN-113372478-A Aldehyde group functionalized cycloolefin-ethylene copolymer and preparation method thereof 万华化学集团股份有限公司 2021-09-10 CN claimed
JP-4722828-B2 2011-07-13 JP claimed
CN-1777624-B Vinyl addition polycyclic olefin polymers prepared with non-olefinic chain transfer agents and uses thereof PROMERUS LLC 2011-05-04 CN claimed
EP-1597287-B1 VINYL ADDITION POLYCYCLIC OLEFIN POLYMERS PREPARED WITH NON-OLEFINIC CHAIN TRANSFER AGENTS AND USES THEREOF PROMERUS LLC (US) 2010-05-05 EP claimed
US-7674847-B2 Vinyl addition polycyclic olefin polymers prepared with non-olefinic chain transfer agents and uses thereof PROMERUS LLC (US) 2010-03-09 US claimed
EP-1597287-A4 VINYL ADDITION POLYCYCLIC OLEFIN POLYMERS PREPARED WITH NON-OLEFINIC CHAIN TRANSFER AGENTS AND USES THEREOF PROMERUS LLC (US) 2008-12-17 EP claimed
US-20070066775-A1 Vinyl addition polycylic olefin polymers prepared using non-olefinic chain transfer agents and uses thereof PROMERUS LLC (US) 2007-03-22 US claimed
CN-1777624-A Vinyl addition polycyclic olefin polymers prepared with non-olefinic chain transfer agents and uses thereof PROMERUS LLC (US) 2006-05-24 CN claimed
EP-1597287-A2 VINYL ADDITION POLYCYCLIC OLEFIN POLYMERS PREPARED WITH NON-OLEFINIC CHAIN TRANSFER AGENTS AND USES THEREOF Promerus LLC (US) 2005-11-23 EP claimed
US-20040229157-A1 Vinyl addition polycyclic olefin polymers prepared with non-olefinic chain transfer agents and uses thereof PROMERUS LLC 2004-11-18 US claimed
WO-2004076495-A2 VINYL ADDITION POLYCYCLIC OLEFIN POLYMERS PREPARED WITH NON-OLEFINIC CHAIN TRANSFER AGENTS AND USES THEREOF PROMERUS LLC (US) 2004-09-10 WO claimed
US-6258508-B1 PHOTORESISTS KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2001-07-10 US claimed
JP-62226943-A None JP disclosed
US-12630738-B2 In-mold coating crosslinkers, compositions, systems, processes and articles RED SPOT PAINT & VARNISH CO., INC. (US) 2026-05-19 US disclosed
US-20260078079-A1 FRAGRANCE AND FLAVOR COMPOSITIONS COMPRISING NORBORNANE AND NORBORNENE DERIVATIVES OSMO LABS PBC (US) 2026-03-19 US disclosed
EP-1085379-A1 Radiation-sensitive resin composition JSR Corporation (JP) 2001-03-21 EP disclosed
EP-1057859-A2 Radiation sensitive resin composition and use of the same in an interlaminar insulating film JSR Corporation (JP) 2000-12-06 EP disclosed
JP-S62226943-A NORBORNENE DERIVATIVE HAVING SUBSTITUTED ETHYL GROUP AND PERFUMERY COMPOSITION CONTAINING SAME NIPPON PETROCHEM CO LTD 1987-10-05 JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12630738-B2 In-mold coating crosslinkers, compositions, systems, processes and articles UROD, DUOX1, PDCD2L KDM4E 1615/4885ALDH1A1 666/4885TSHR 4843/4885
US-20260078079-A1 FRAGRANCE AND FLAVOR COMPOSITIONS COMPRISING NORBORNANE AND NORBORNENE DERIVATIVES CBR1, CBR3, TAS2R1 KDM4E 4643/4885ALDH1A1 804/4885TSHR 1119/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.