Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | PPARA | Q07869 | 2/20 | 0.40 |
| ▸ | PLK1 | P53350 | 1/20 | 0.40 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | CETP | P11597 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | INPPL1 | O15357 | 1/20 | 0.36 |
| ▸ | INPP5B | P32019 | 1/20 | 0.36 |
| ▸ | INPP5A | Q14642 | 1/20 | 0.36 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.36 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.36 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL456733 | 0.86 | SRC (0.45) | PLK1ALOX5PTGS2CETPTSHR | |
| SCHEMBL18141467 | 0.84 | THRA (0.56) | THRATHRBPPARAPLK1LIPG | |
| SCHEMBL18139228 | 0.84 | THRA (0.56) | THRATHRBPPARAPLK1LIPG | |
| SCHEMBL18140210 | 0.84 | THRA (0.56) | THRATHRBPPARAPLK1LIPG | |
| SCHEMBL1100816 | 0.84 | THRA (0.56) | THRATHRBPPARAPLK1LIPG | |
| SCHEMBL248072 | 0.84 | THRA (0.56) | THRATHRBPPARAPLK1LIPG | |
| SCHEMBL18141719 | 0.84 | THRA (0.56) | THRATHRBPPARAPLK1LIPG | |
| SCHEMBL18139782 | 0.84 | THRA (0.56) | THRATHRBPPARAPLK1LIPG | |
| SCHEMBL18140912 | 0.84 | THRA (0.56) | THRATHRBPPARAPLK1LIPG | |
| SCHEMBL10878272 | 0.84 | THRA (0.56) | THRATHRBPPARAPLK1LIPG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0135726-A2 | Flame retardant polyolefin compositions, articles, and process of manufacture | GENERAL ELECTRIC COMPANY (US) | 1985-04-03 | — | — | EP | disclosed |