SCHEMBL456733

SCHEMBL456733

CCCCCCCCCCCCc1cc(C)cc(CCCCCCCCCCCC)c1OP(=O)(O)O

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SRC P12931 2/20 0.45
ALOX5 P09917 6/20 0.42
ENPP2 Q13822 1/20 0.41
PLK1 P53350 1/20 0.40
LPAR3 Q9UBY5 3/20 0.40
LPAR1 Q92633 2/20 0.40
LPAR2 Q9HBW0 2/20 0.40
TYR P14679 2/20 0.38
MEN1 O00255 1/20 0.38
TP53 P04637 1/20 0.38
CYP3A4 P08684 1/20 0.38
MAPT P10636 1/20 0.38
ALOX15 P16050 1/20 0.38
TSHR P16473 1/20 0.38
HTT P42858 1/20 0.38
KMT2A Q03164 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
S1PR2 O95136 2/20 0.38
S1PR4 O95977 2/20 0.38
S1PR1 P21453 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10979679 0.86 THRA (0.44) ALOX5PLK1TSHRS1PR2S1PR4
SCHEMBL27750960 0.81 NPC1 (0.41) SRCENPP2PLK1CYP3A4HTT
SCHEMBL11619328 0.81 GAA (0.41) ALOX5ENPP2PLK1TYRMEN1
SCHEMBL3683527 0.81 GAA (0.41) ALOX5ENPP2PLK1TYRMEN1
SCHEMBL11619330 0.78 LIPG (0.46) ALOX5ENPP2PLK1S1PR2S1PR4
SCHEMBL8461311 0.76 PLK1 (0.35) SRCALOX5ENPP2PLK1LPAR3
SCHEMBL8852795 0.76 PLK1 (0.35) SRCALOX5ENPP2PLK1LPAR3
SCHEMBL29174980 0.76 TYR (0.45) ALOX5ENPP2PLK1LPAR3LPAR1
SCHEMBL29045393 0.76 TYR (0.45) ALOX5ENPP2PLK1LPAR3LPAR1
SCHEMBL6318720 0.76 NPC1 (0.37) SRCENPP2PLK1CYP3A4HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 298 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070149661-A1 POLYCARBONATE COMPOSITION, METHOD OF MANUFACTURE THEREOF AND ARTICLES COMPRISING THE SAME CITIBANK, N.A., AS COLLATERAL AGENT 2007-06-28 US claimed
US-12570848-B2 Scratch-resistant high impact strength PMMA compositions SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2026-03-10 US disclosed
US-12403437-B2 Method for producing nanodiamonds doped with group 14 element, and method for purifying same DAICEL CORPORATION (JP) 2025-09-02 US disclosed
US-12351463-B2 Heteroatom-doped nanodiamond DAICEL CORPORATION (JP) 2025-07-08 US disclosed
EP-4172269-B1 THERMOPLASTIC COMPOSITIONS WITH IMPROVED HYDROLYTIC AND HEAT STABILITY SHPP GLOBAL TECH BV (NL) 2025-05-28 EP disclosed
WO-2025104593-A1 PFAS-FREE FLAME RETARDANT, IMPACT RESISTANT AND CHEMICAL RESISTANT POLYCARBONATE COMPOSITIONS SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2025-05-22 WO disclosed
US-20250002355-A1 HETEROATOM-DOPED NANODIAMOND PARTICLES AND METHOD FOR PRODUCING HETEROATOM-DOPED NANODIAMOND PARTICLES DAICEL CORPORATION (JP) 2025-01-02 US disclosed
WO-2024219059-A1 NV CENTER-CONTAINING NANODIAMOND PARTICLE AND METHOD FOR PRODUCING SAME 株式会社ダイセル 2024-10-24 WO disclosed
EP-3390469-B1 METHOD FOR ISOMER REDUCTION DURING POLYMERIZATION AND SYSTEM FOR ACCOMPLISHING THE SAME DOW GLOBAL TECHNOLOGIES LLC (US) 2024-09-04 EP disclosed
EP-4382481-A1 HETEROATOM-DOPED NANODIAMOND PARTICLES AND METHOD FOR PRODUCING HETEROATOM-DOPED NANODIAMOND PARTICLES Daicel Corporation (JP) 2024-06-12 EP disclosed
EP-0055473-A1 Resin compositions SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1982-07-07 EP disclosed
EP-0043838-A4 POLYPHENYLENE OXIDE/PLASTICIZER/HYDROGENATED RADIAL TELEBLOCK COPOLYMER BLENDS. GEN ELECTRIC (US) 1982-04-29 EP disclosed
US-4313864-A IMPACT RESISTANCE GENERAL ELECTRIC COMPANY (US) 1982-02-02 US disclosed
EP-0043838-A1 POLYPHENYLENE OXIDE/PLASTICIZER/HYDROGENATED RADIAL TELEBLOCK COPOLYMER BLENDS GENERAL ELECTRIC COMPANY (US) 1982-01-20 EP disclosed
WO-1981002160-A1 POLYPHENYLENE OXIDE/PLASTICIZER/HYDROGENATED RADIAL TELEBLOCK COPOLYMER BLENDS GEN ELECTRIC (US) 1981-08-06 WO disclosed
US-4254011-A CONTAINING A TWO-PHASE CROSSLINKED POLYACRYLATE BAYER AKTIENGESELLSCHAFT (DE) 1981-03-03 US disclosed
US-4154712-A VINYLAROMATIC-CONJUGATED DIENE BLOCK POLYMER GENERAL ELECTRIC COMPANY (US) 1979-05-15 US disclosed
US-4136089-A 2,2-DIETHYL-PROPANE-1,3-DIOL BAYER AKTIENGESELLSCHAFT (DE) 1979-01-23 US disclosed
US-4107149-A Poly(ethylene/alkylene) terephthalates which crystallize rapidly BAYER AKTIENGESELLSCHAFT (DE) 1978-08-15 US disclosed
US-4086212-A ESTERIFICATION OR TRANSESTERIFICATION BAYER AKTIENGESELLSCHAFT (DT) 1978-04-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12570848-B2 Scratch-resistant high impact strength PMMA compositions PCNA, COL2A1, COL1A1 SRC 1022/4885ALOX5 3823/4885ENPP2 4081/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.