Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.85 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.85 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.85 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.85 |
| ▸ | IGF1R | P08069 | 3/20 | 0.77 |
| ▸ | GAA | P10253 | 1/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7271980 | 0.99 | MEN1 (0.83) | MEN1KMT2AOPRM1OPRD1IGF1R | |
| SCHEMBL10992721 | 0.92 | MEN1 (1.00) | MEN1KMT2AOPRM1OPRD1IGF1R | |
| Hydrochloric Acid SCHEMBL10990138 | 0.91 | MEN1 (0.97) | MEN1KMT2AOPRM1OPRD1IGF1R | |
| SCHEMBL8196250 | 0.84 | OPRM1 (0.62) | MEN1KMT2AOPRM1OPRD1KDM4E | |
| SCHEMBL10986157 | 0.83 | KMT2A (0.71) | MEN1KMT2AOPRM1OPRD1IGF1R | |
| SCHEMBL10746494 | 0.82 | GAA (0.82) | MEN1KMT2AOPRM1OPRD1IGF1R | |
| SCHEMBL2796836 | 0.82 | GAA (0.82) | MEN1KMT2AOPRM1OPRD1IGF1R | |
| Hydrochloric Acid SCHEMBL7271738 | 0.82 | KMT2A (0.69) | MEN1KMT2AOPRM1OPRD1IGF1R | |
| Hydrochloric Acid SCHEMBL10987589 | 0.80 | KMT2A (0.71) | MEN1KMT2AOPRM1OPRD1IGF1R | |
| SCHEMBL5319116 | 0.79 | MEN1 (0.54) | MEN1KMT2AOPRM1OPRD1IGF1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-58124776-A | — | — | None | — | — | JP | disclosed |
| US-4528194-A | 2-(4-Diphenylmethylpiperazinyl)-1-phenyl alkanol or their salts, a process for their production and a cerebral circulation-improving drug | NIPPON CHEMIPHAR CO., LTD. (JP) | 1985-07-09 | — | — | US | disclosed |
| JP-S58124776-A | NOVEL PIPERAZINE DERIVATIVE, ITS PREPARATION AND AMELIORANT FOR CEREBRAL CIRCULATION CONTAINING THE SAME | NIPPON CHEMIPHAR CO LTD | 1983-07-25 | — | — | JP | disclosed |