Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.54 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | GFER | P55789 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.51 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.51 |
| ▸ | HTR2A | P28223 | 2/20 | 0.51 |
| ▸ | HRH1 | P35367 | 2/20 | 0.51 |
| ▸ | DRD3 | P35462 | 2/20 | 0.51 |
| ▸ | HTR2B | P41595 | 2/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.51 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.51 |
| ▸ | DRD2 | P14416 | 1/20 | 0.51 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12489451 | 0.91 | OPRM1 (0.59) | MEN1OPRM1KMT2AKCNA3OPRD1 | |
| SCHEMBL8196250 | 0.84 | OPRM1 (0.62) | MEN1OPRM1KMT2AOPRD1MAPT | |
| SCHEMBL10979769 | 0.79 | MEN1 (0.85) | MEN1OPRM1KMT2AOPRD1IGF1R | |
| Belarizine SCHEMBL2108057 | 0.79 | ATM (0.73) | MEN1OPRM1KMT2AOPRD1MAPT | |
| SCHEMBL172597 | 0.78 | KMT2A (0.62) | MEN1OPRM1KMT2AOPRD1MAPT | |
| Hydrochloric Acid SCHEMBL7271980 | 0.78 | MEN1 (0.83) | MEN1OPRM1KMT2AOPRD1IGF1R | |
| SCHEMBL1491229 | 0.78 | OPRD1 (0.65) | MEN1OPRM1KMT2AOPRD1MAPT | |
| SCHEMBL7647399 | 0.77 | KMT2A (0.57) | MEN1OPRM1KMT2AOPRD1MAPT | |
| SCHEMBL7991683 | 0.76 | HTR1A (0.70) | MEN1OPRM1KMT2AOPRD1TDP1 | |
| SCHEMBL9720751 | 0.76 | KCNH2 (0.71) | MEN1OPRM1KMT2AOPRD1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1610792-B1 | CALCIUM CHANNEL BLOCKERS COMPRISING TWO BENZHYDRIL MOIETIES | NEUROMED TECH INC (CA) | 2007-10-10 | — | — | EP | claimed |