Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C4 | P17516 | 1/20 | 0.52 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.52 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.52 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.45 |
| ▸ | HPGD | P15428 | 4/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | CASP1 | P29466 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | CFD | P00746 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL1097098 | 0.98 | AKR1C4 (0.50) | AKR1C4AKR1C3AKR1C2AKR1C1KDM4E | |
| SCHEMBL1097096 | 0.86 | ABCB11 (0.41) | AKR1C4AKR1C3AKR1C2AKR1C1KDM4E | |
| SCHEMBL14339912 | 0.85 | AKR1C4 (0.47) | AKR1C4AKR1C3AKR1C2AKR1C1KDM4E | |
| SCHEMBL4645395 | 0.85 | ABCB11 (0.49) | KDM4EALDH1A1HSD17B10TSHRTP53 | |
| SCHEMBL18871612 | 0.83 | ABCB11 (0.45) | AKR1C4AKR1C3AKR1C2AKR1C1KDM4E | |
| SCHEMBL1096935 | 0.83 | HPGD (0.45) | AKR1C4AKR1C3AKR1C2AKR1C1KDM4E | |
| SCHEMBL1096938 | 0.82 | KDM4E (0.45) | AKR1C4AKR1C3AKR1C2AKR1C1KDM4E | |
| Hydrochloric Acid SCHEMBL1098712 | 0.82 | HPGD (0.44) | AKR1C4AKR1C3AKR1C2AKR1C1KDM4E | |
| SCHEMBL30084374 | 0.81 | ACLY (0.56) | AKR1C4AKR1C3AKR1C2AKR1C1KDM4E | |
| SCHEMBL423692 | 0.81 | ACLY (0.56) | AKR1C4AKR1C3AKR1C2AKR1C1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105218393-A | The method of synthesis mycotoxin absorbant and preparation and the described synthesis mycotoxin absorbant of use | ALLTECH INC | 2016-01-06 | — | — | CN | claimed |
| EP-2470894-B1 | SYNTHETIC MYCOTOXIN ADSORBENTS AND METHODS OF MAKING AND UTILIZING THE SAME | ALLTECH INC (US) | 2021-12-29 | — | — | EP | disclosed |
| EP-2470894-B1 | SYNTHETIC MYCOTOXIN ADSORBENTS AND METHODS OF MAKING AND UTILIZING THE SAME | ALLTECH INC (US) | 2021-12-29 | — | — | EP | disclosed |
| CN-102549424-B | Synthetic mycotoxin adsorbents and methods of making and using the same | ALLTECH, INC. (US) | 2016-01-13 | — | — | CN | disclosed |
| CN-105218393-A | The method of synthesis mycotoxin absorbant and preparation and the described synthesis mycotoxin absorbant of use | ALLTECH INC | 2016-01-06 | — | — | CN | disclosed |
| CN-104190378-A | SYNTHETIC MYCOTOXIN ADSORBENTS AND METHODS OF MAKING AND UTILIZING THE SAME | ALLTECH INC | 2014-12-10 | — | — | CN | disclosed |
| US-RE45274-E1 | Synthetic mycotoxin adsorbents and methods of making and utilizing the same | ALLTECH, INC. (US) | 2014-12-02 | — | — | US | disclosed |
| US-8426541-B2 | Synthetic mycotoxin adsorbents and methods of making and utilizing the same | ALLTECH, INC. (US) | 2013-04-23 | — | — | US | disclosed |
| US-8426541-B2 | Synthetic mycotoxin adsorbents and methods of making and utilizing the same | ALLTECH, INC. (US) | 2013-04-23 | — | — | US | disclosed |
| US-8324405-B2 | Chromene derivatives and use thereof as HIF hydroxylase activity inhibitors | FIBROGEN, INC. (US) | 2012-12-04 | — | — | US | disclosed |
| US-20120214897-A1 | SYNTHETIC MYCOTOXIN ADSORBENTS AND METHODS OF MAKING AND UTILIZING THE SAME | ALLTECH, INC. (US) | 2012-08-23 | — | — | US | disclosed |
| US-20120214897-A1 | SYNTHETIC MYCOTOXIN ADSORBENTS AND METHODS OF MAKING AND UTILIZING THE SAME | ALLTECH, INC. (US) | 2012-08-23 | — | — | US | disclosed |
| EP-2470894-A1 | SYNTHETIC MYCOTOXIN ADSORBENTS AND METHODS OF MAKING AND UTILIZING THE SAME | Alltech, Inc. (US) | 2012-07-04 | — | — | EP | disclosed |
| CN-102549424-A | Synthetic mycotoxin adsorbents and methods of making and using the same | ALLTECH INC | 2012-07-04 | — | — | CN | disclosed |
| US-8153737-B2 | Synthetic mycotoxin adsorbents and methods of making and utilizing the same | ALLTECH, INC. (US) | 2012-04-10 | — | — | US | disclosed |
| WO-2011031562-A1 | SYNTHETIC MYCOTOXIN ADSORBENTS AND METHODS OF MAKING AND UTILIZING THE SAME | ALLTECH, INC. (US) | 2011-03-17 | — | — | WO | disclosed |
| US-20110054132-A1 | SYNTHETIC MYCOTOXIN ADSORBENTS AND METHODS OF MAKING AND UTILIZING THE SAME | ALLTECH, INC. (US) | 2011-03-03 | — | — | US | disclosed |
| US-20110054132-A1 | SYNTHETIC MYCOTOXIN ADSORBENTS AND METHODS OF MAKING AND UTILIZING THE SAME | ALLTECH, INC. (US) | 2011-03-03 | — | — | US | disclosed |
| US-20100331400-A1 | CHROMENE DERIVATIVES AND USE THEREOF AS HIF HYDROXYLASE ACTIVITY INHIBITORS | FIBROGEN, INC. | 2010-12-30 | — | — | US | disclosed |
| WO-2009100250-A1 | CHROMENE DERIVATIVES AND USE THEREOF AS HIF HYDROXYLASE ACTIVITY INHIBITORS | FIBROGEN, INC. (US) | 2009-08-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100331400-A1 | CHROMENE DERIVATIVES AND USE THEREOF AS HIF HYDROXYLASE ACTIVITY INHIBITORS | HIF1AN, HIF1A, EGLN2 | AKR1C4 531/4885AKR1C3 330/4885AKR1C2 253/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.