Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.55 |
| ▸ | MEN1 | O00255 | 5/20 | 0.55 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.55 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.55 |
| ▸ | IGF1R | P08069 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7265511 | 0.99 | KMT2A (0.54) | KMT2AMEN1OPRM1OPRD1IGF1R | |
| SCHEMBL10986157 | 0.84 | KMT2A (0.71) | KMT2AMEN1OPRM1OPRD1IGF1R | |
| Hydrochloric Acid SCHEMBL7271738 | 0.83 | KMT2A (0.69) | KMT2AMEN1OPRM1OPRD1IGF1R | |
| SCHEMBL10980359 | 0.81 | MEN1 (0.59) | KMT2AMEN1OPRM1OPRD1IGF1R | |
| Hydrochloric Acid SCHEMBL7272686 | 0.81 | MEN1 (0.57) | KMT2AMEN1OPRM1OPRD1IGF1R | |
| SCHEMBL10987926 | 0.79 | KMT2A (0.50) | KMT2AMEN1OPRM1OPRD1IGF1R | |
| SCHEMBL11035863 | 0.79 | MEN1 (0.51) | KMT2AMEN1KCNH2LMNANPSR1 | |
| Hydrochloric Acid SCHEMBL7265013 | 0.78 | KMT2A (0.49) | KMT2AMEN1OPRM1OPRD1IGF1R | |
| SCHEMBL10988175 | 0.77 | MEN1 (0.59) | KMT2AMEN1OPRM1OPRD1IGF1R | |
| SCHEMBL10992721 | 0.73 | MEN1 (1.00) | KMT2AMEN1OPRM1OPRD1IGF1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4528194-A | 2-(4-Diphenylmethylpiperazinyl)-1-phenyl alkanol or their salts, a process for their production and a cerebral circulation-improving drug | NIPPON CHEMIPHAR CO., LTD. (JP) | 1985-07-09 | — | — | US | disclosed |