Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9017102 | 0.73 | TSHR (0.43) | TSHR | |
| SCHEMBL11813341 | 0.71 | — | — | |
| SCHEMBL11068747 | 0.71 | — | — | |
| SCHEMBL1583127 | 0.70 | — | — | |
| SCHEMBL7559622 | 0.70 | — | — | |
| SCHEMBL27940802 | 0.69 | TSHR (0.52) | TSHR | |
| Ammonia Solution, Strong SCHEMBL10667289 | 0.69 | — | — | |
| SCHEMBL11770875 | 0.66 | — | — | |
| SCHEMBL9776345 | 0.66 | — | — | |
| SCHEMBL8408015 | 0.65 | TSHR (0.45) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4510319-A | ROGANOLEPTICS | FRITZSCHE DODGE & OLCOTT INC. (US) | 1985-04-09 | — | — | US | disclosed |