SCHEMBL9017102

SCHEMBL9017102

C=CC(=C)CCC(Cl)C(=C)C

nearest known ligand 0.43

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.43
ALDH1A1 P00352 1/20 0.32
TP53 P04637 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8408015 0.76 TSHR (0.45) TSHRALDH1A1TP53
SCHEMBL19987848 0.76
SCHEMBL24261133 0.74 TSHR (0.43) TSHRALDH1A1TP53
SCHEMBL10980652 0.73 TSHR (0.37) TSHR
SCHEMBL24354403 0.72 TSHR (0.38) TSHR
SCHEMBL1583127 0.72
SCHEMBL21386449 0.71 TSHR (0.41) TSHR
SCHEMBL21386450 0.71 TSHR (0.41) TSHR
SCHEMBL10732290 0.71 ALDH1A1 (0.34) ALDH1A1
SCHEMBL10981683 0.70

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0152324-B1 TETRAENE, ITS PREPARATION AND ITS USE RHONE-POULENC SANTE (FR) 1986-11-12 EP claimed
US-4543433-A Tetraene, its preparation and its use RHONE-POULENC SANTE (FR) 1985-09-24 US claimed
US-12195561-B2 Bissilylamino-functionalized conjugated dienes, their preparation and their use in the production of rubbers SYNTHOS S.A. (PL) 2025-01-14 US disclosed
CN-113329890-B Bis-silylamino functionalized conjugated dienes, preparation thereof and use thereof in rubber production 西索斯公司 2023-10-20 CN disclosed
EP-3911525-B1 BISSILYLAMINO-FUNCTIONALIZED CONJUGATED DIENES, THEIR PREPARATION AND THEIR USE IN THE PRODUCTION OF RUBBERS Synthos Sa (PL) 2023-03-08 EP disclosed
US-11312843-B2 Bissilylaminosilyl-functionalized conjugated dienes and their use in the production of rubbers SYNTHOS DWORY 7 SPOLKA Z OGRANICZONA ODPOWIEDZIALNOSCIA SPOLKA JAWNA 2022-04-26 US disclosed
US-20220119555-A1 BISSILYLAMINO-FUNCTIONALIZED CONJUGATED DIENES, THEIR PREPARATION AND THEIR USE IN THE PRODUCTION OF RUBBERS SYNTHOS DWORY 7 SPOLKA Z OGRANICZONA ODPOWIEDZIALNOSCIA (PL) 2022-04-21 US disclosed
US-20220119555-A1 BISSILYLAMINO-FUNCTIONALIZED CONJUGATED DIENES, THEIR PREPARATION AND THEIR USE IN THE PRODUCTION OF RUBBERS SYNTHOS DWORY 7 SPOLKA Z OGRANICZONA ODPOWIEDZIALNOSCIA (PL) 2022-04-21 US disclosed
EP-3911525-A1 BISSILYLAMINO-FUNCTIONALIZED CONJUGATED DIENES, THEIR PREPARATION AND THEIR USE IN THE PRODUCTION OF RUBBERS Synthos S.A. (PL) 2021-11-24 EP disclosed
CN-113329890-A Bis-silylamino-functionalized conjugated diolefins, their preparation and their use in the production of rubbers 西索斯公司 2021-08-31 CN disclosed
EP-3548499-B1 BISSILYLAMINOSILYL-FUNCTIONALIZED CONJUGATED DIENES AND THEIR USE IN THE PRODUCTION OF RUBBERS SYNTHOS DWORY 7 SPOLKA Z OGRANICZONA ODPOWIEDZIALNOSCIA SPOLKA JAWNA (PL) 2020-09-23 EP disclosed
US-4693849-A Preparation of unsaturated compounds RHONE-POULENC SANTE (FR) 1987-09-15 US disclosed
US-4615838-A Unsaturated compounds and their preparation RHONE-POULENC SANTE (FR) 1986-10-07 US disclosed
US-4543433-A Tetraene, its preparation and its use RHONE-POULENC SANTE (FR) 1985-09-24 US disclosed
US-4293497-A ALKYLATION CATALYSTS, VIATMIN E SCM CORPORATION (US) 1981-10-06 US disclosed
US-4292454-A INTERMEDIATES FOR VITAMIN E SCM CORPORATION (US) 1981-09-29 US disclosed
US-4292459-A Coupling reaction involving a Grignard and allylic halide SCM CORPORATION (US) 1981-09-29 US disclosed
US-4228313-A TO PREPARE A REARRANGED UNSATURATED HYDROCARBON SCM CORPORATION (US) 1980-10-14 US disclosed
US-4221742-A Coupling reaction involving a Grignard and allylic halide SCM CORPORATION (US) 1980-09-09 US disclosed
US-4168271-A Unsaturated vitamin E intermediates--dehydro and didehydro α-tocopherols SCM CORPORATION (US) 1979-09-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12195561-B2 Bissilylamino-functionalized conjugated dienes, their preparation and their use in the production of rubbers CARM1, ILK, RIF1 TSHR 3100/4885ALDH1A1 473/4885TP53 2131/4885
US-20220119555-A1 BISSILYLAMINO-FUNCTIONALIZED CONJUGATED DIENES, THEIR PREPARATION AND THEIR USE IN THE PRODUCTION OF RUBBERS CARM1, ILK, RIF1 TSHR 3100/4885ALDH1A1 473/4885TP53 2131/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.