SCHEMBL8408015

SCHEMBL8408015

C=CC(=C)CCC(O)C(=C)C

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.45
ALDH1A1 P00352 1/20 0.33
TP53 P04637 1/20 0.33
NDUFS8 O00217 1/20 0.30
COXFA4 O00483 1/20 0.30
NDUFAB1 O14561 1/20 0.30
NDUFA1 O15239 1/20 0.30
NDUFS4 O43181 1/20 0.30
NDUFB5 O43674 1/20 0.30
NDUFB3 O43676 1/20 0.30
NDUFC1 O43677 1/20 0.30
NDUFA2 O43678 1/20 0.30
NDUFS5 O43920 1/20 0.30
NDUFS7 O75251 1/20 0.30
NDUFS2 O75306 1/20 0.30
NDUFS6 O75380 1/20 0.30
NDUFB1 O75438 1/20 0.30
NDUFS3 O75489 1/20 0.30
NDUFB6 O95139 1/20 0.30
NDUFA3 O95167 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11800702 0.83 TSHR (0.53) TSHRALDH1A1NDUFS8COXFA4NDUFAB1
SCHEMBL11804538 0.83 TSHR (0.53) TSHRALDH1A1NDUFS8COXFA4NDUFAB1
SCHEMBL24261133 0.76 TSHR (0.43) TSHRALDH1A1TP53
SCHEMBL9017102 0.76 TSHR (0.43) TSHRALDH1A1TP53
SCHEMBL11412050 0.75 HSD17B10 (0.32) NDUFS8COXFA4NDUFAB1NDUFA1NDUFS4
SCHEMBL15316377 0.74 NDUFS8 (0.36) NDUFS8COXFA4NDUFAB1NDUFA1NDUFS4
SCHEMBL8531998 0.74 HSD17B10 (0.32)
SCHEMBL1583127 0.73
SCHEMBL5521542 0.73 NDUFS8 (0.35) NDUFS8COXFA4NDUFAB1NDUFA1NDUFS4
SCHEMBL5521538 0.73 NDUFS8 (0.35) NDUFS8COXFA4NDUFAB1NDUFA1NDUFS4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-11279103-A None JP disclosed
JP-H11279103-A PRODUCTION OF UNSATURATED CARBOXYLIC ACID ESTER AND PRODUCTION OF BETA-SINENSAL BY USING THE UNSATURATED CARBOXYLIC ACID ESTER AS INTERMEDIATE SODA AROMATIC CO LTD 1999-10-12 JP disclosed
EP-0024095-B1 TOTAL SYNTHESIS OF (1RS, 4SR, 5RS)-4-(4,8-DIMETHYL-5-HYDROXY-7-NONENYL)-4-METHYL-3,8-DIOXABICYCLO (3.2.1) OCTANE-1-ACETIC ACID AND INTERMEDIATES ORTHO PHARMACEUTICAL CORPORATION (US) 1984-09-26 EP disclosed
EP-0024095-A1 Total synthesis of (1RS, 4SR, 5RS)-4-(4,8-dimethyl-5-hydroxy-7-nonenyl)-4-methyl-3,8-dioxabicyclo (3.2.1) octane-1-acetic acid and intermediates ORTHO PHARMACEUTICAL CORPORATION (US) 1981-02-25 EP disclosed
US-4215048-A Total synthesis of (1RS, 4SR, 5RS)-4-(4,8-dimethyl-5-hydroxy-7-nonenyl)-4-methyl-3,8-dioxabicyclo[3.2.1]octane-1-acetic acid ORTHO PHARMACEUTICAL CORPORATION (US) 1980-07-29 US disclosed
US-4031161-A Process for producing mixture containing 4-(4'-methyl-4'-hydroxyamyl)-Δ3 -cyclohexene carboxaldehyde INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1977-06-21 US disclosed
US-4007137-A Process for producing mixture containing 4-(4-methyl-4-hydroxyamyl)Δ3 -cyclohexenecarboxaldehyde, product produced, and its perfume uses INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1977-02-08 US disclosed
US-3947505-A 1-Halo-dodeca-tri(tetra)-ene GIVAUDAN CORPORATION (US) 1976-03-30 US disclosed
US-3943177-A Compounds of the sinensal type, intermediates and process therefor GIVAUDAN CORPORATION (US) 1976-03-09 US disclosed