Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Tetrachloroethylene. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.71 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tetrachloroethylene SCHEMBL28103404 | 0.86 | — | — | |
| Hypochlorous Acid SCHEMBL7999526 | 0.84 | — | — | |
| Tetrachloroethylene SCHEMBL6416073 | 0.84 | — | — | |
| Tetrachloroethylene SCHEMBL1332648 | 0.84 | — | — | |
| Tetrachloroethylene SCHEMBL23022 | 0.84 | — | — | |
| Tetrachloroethylene SCHEMBL8027970 | 0.84 | TSHR (1.00) | TSHR | |
| Tetrachloroethylene SCHEMBL8508058 | 0.84 | TSHR (1.00) | TSHR | |
| Tetrachloroethylene SCHEMBL1333241 | 0.84 | — | — | |
| Hypochlorous Acid SCHEMBL6387943 | 0.84 | TSHR (0.43) | TSHR | |
| Tetrachloroethylene SCHEMBL9402096 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4493790-A | Organoleptic use of isopropyl tetramethylindanes | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 1985-01-15 | — | — | US | disclosed |
| US-4466908-A | Isopropyl tetramethylindan musk, organoleptic use thereof | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 1984-08-21 | — | — | US | disclosed |