Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Tetrachloroethylene. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tetrachloroethylene SCHEMBL10980902 | 0.86 | TSHR (0.71) | — | |
| Tetrachloroethylene SCHEMBL8508058 | 0.84 | TSHR (1.00) | — | |
| Tetrachloroethylene SCHEMBL1333241 | 0.84 | — | — | |
| Tetrachloroethylene SCHEMBL6416073 | 0.84 | — | — | |
| Tetrachloroethylene SCHEMBL1332648 | 0.84 | — | — | |
| Hypochlorous Acid SCHEMBL8973787 | 0.84 | — | — | |
| Tetrachloroethylene SCHEMBL23022 | 0.84 | — | — | |
| Tetrachloroethylene SCHEMBL8027970 | 0.84 | TSHR (1.00) | — | |
| Tetrachloroethylene SCHEMBL170654 | 0.77 | — | — | |
| Tetrachloroethylene SCHEMBL10592952 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105949857-A | Antibacterial drying and protecting treatment agent for painting and calligraphy artistic works | 孟根森 | 2016-09-21 | — | — | CN | claimed |