Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | KMO | O15229 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | KDM1A | O60341 | 2/20 | 0.33 |
| ▸ | MAOA | P21397 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.32 |
| ▸ | AKT1 | P31749 | 1/20 | 0.32 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL310551 | 0.81 | PARP1 (0.39) | PARP1KMT2AMEN1CYP2C19KMO | |
| SCHEMBL2539492 | 0.80 | ATM (0.55) | PARP1KMOL3MBTL1ALDH1A1SMN1; SMN2 | |
| SCHEMBL2282510 | 0.79 | KMO (0.56) | PARP1KMT2AMEN1KMOTSHR | |
| SCHEMBL5423204 | 0.77 | PARP1 (0.49) | PARP1KMOL3MBTL1KDM1AALDH1A1 | |
| SCHEMBL13901589 | 0.75 | PARP1 (0.46) | PARP1KMOL3MBTL1TSHRKDM1A | |
| SCHEMBL6697278 | 0.75 | PARP1 (0.68) | PARP1CYP2C19L3MBTL1TSHRKDM1A | |
| SCHEMBL13962635 | 0.75 | PARP1 (0.46) | PARP1CYP2C19KMOL3MBTL1HTT | |
| SCHEMBL5429553 | 0.75 | PARP1 (0.39) | PARP1KMT2AMEN1CYP2C19KMO | |
| SCHEMBL4246223 | 0.75 | PARP1 (0.46) | PARP1KMT2AMEN1KMOHTT | |
| SCHEMBL814654 | 0.73 | MEN1 (0.52) | KMT2AMEN1KMOL3MBTL1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4504491-A | INSECTICIDE | NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) | 1985-03-12 | — | — | US | disclosed |