Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 8/20 | 0.45 |
| ▸ | CES1 | P23141 | 2/20 | 0.42 |
| ▸ | DAGLA | Q9Y4D2 | 2/20 | 0.42 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 2/20 | 0.40 |
| ▸ | F7 | P08709 | 2/20 | 0.40 |
| ▸ | F3 | P13726 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | ECE1 | P42892 | 1/20 | 0.40 |
| ▸ | SGMS1 | Q86VZ5 | 1/20 | 0.40 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.40 |
| ▸ | MUS81 | Q96NY9 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10988111 | 1.00 | FAAH (0.45) | FAAHCES1DAGLACYP11B1MMP2 | |
| SCHEMBL10982482 | 0.95 | F7 (0.45) | FAAHCES1DAGLAMMP2F7 | |
| SCHEMBL10986240 | 0.90 | BID (0.43) | FAAHCES1DAGLACYP11B1MMP2 | |
| SCHEMBL10982801 | 0.86 | CYP11B1 (0.46) | CYP11B1HSD17B10SAE1 | |
| SCHEMBL29907810 | 0.86 | CYP11B1 (0.46) | CYP11B1HSD17B10SAE1 | |
| SCHEMBL9440243 | 0.86 | CYP11B1 (0.46) | CYP11B1HSD17B10SAE1 | |
| SCHEMBL27764936 | 0.84 | CYP11B1 (0.47) | CYP11B1HSD17B10SAE1 | |
| SCHEMBL5233261 | 0.82 | CYP11B1 (0.48) | CYP11B1KDM4E | |
| SCHEMBL10982827 | 0.80 | CYSLTR2 (0.39) | FAAHCES1DAGLA | |
| SCHEMBL10982754 | 0.80 | CYSLTR2 (0.39) | FAAHCES1DAGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4555520-A | 2-Pyridylcarboxamides which inhibit arachidonic acid release | E. R. SQUIBB & SONS, INC. (US) | 1985-11-26 | — | — | US | disclosed |