Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | HTT | P42858 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.53 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | XBP1 | P17861 | 1/20 | 0.53 |
| ▸ | MPI | P34949 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | CA1 | P00915 | 2/20 | 0.48 |
| ▸ | CA2 | P00918 | 2/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | CA3 | P07451 | 1/20 | 0.48 |
| ▸ | CA6 | P23280 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11310744 | 0.84 | ALDH1A1 (0.51) | ALDH1A1SMN1; SMN2HTTLMNAMAPK1 | |
| SCHEMBL6474700 | 0.83 | ALDH1A1 (0.50) | ALDH1A1SMN1; SMN2HTTLMNAMAPK1 | |
| SCHEMBL7542039 | 0.79 | ALDH1A1 (0.47) | ALDH1A1SMN1; SMN2HTTLMNAMAPK1 | |
| SCHEMBL11528365 | 0.79 | ALDH1A1 (0.47) | ALDH1A1SMN1; SMN2HTTLMNAMAPK1 | |
| SCHEMBL28706040 | 0.79 | ALDH1A1 (0.47) | ALDH1A1SMN1; SMN2HTTLMNAMAPK1 | |
| SCHEMBL91998 | 0.79 | ALDH1A1 (0.47) | ALDH1A1SMN1; SMN2HTTLMNAMAPK1 | |
| SCHEMBL2535039 | 0.79 | GAA (0.54) | ALDH1A1SMN1; SMN2HTTLMNAMAPK1 | |
| SCHEMBL7186972 | 0.78 | GAA (0.59) | ALDH1A1SMN1; SMN2HTTLMNAMAPK1 | |
| SCHEMBL6490 | 0.78 | GAA (0.59) | ALDH1A1SMN1; SMN2HTTMAPTGAA | |
| SCHEMBL13673554 | 0.78 | F2 (0.55) | ALDH1A1SMN1; SMN2HTTLMNAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4558043-A | Heterocyclicamino containing benzofurans and 2,3-dihydrobenzofurans, compositions and use | CIBA GEIGY CORPORATION (US) | 1985-12-10 | — | — | US | disclosed |